Antisense modulation of bcl-x expression

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United States of America Patent

PATENT NO 7148204
SERIAL NO

10302262

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Abstract

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Compositions and methods are provided for modulating the expression of bcl-x. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding bcl-x are preferred. Methods of using these compounds for modulation of bcl-x expression and for treatment of diseases associated with expression of bcl-x are also provided. Methods of sensitizing cells to apoptotic stimuli are also provided.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INC2855 GAZELLE COURT CARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, C Frank Carlsbad, CA 412 7677
Dean, Nicholas M Olivenhain, CA 126 2851
Monia, Brett P Encinitas, CA 303 5836
Nickoloff, Brian J Burr Ridge, IL 8 584
Zhang, Vivian Q San Diego, CA 1 138

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