Frit material and bonding method for microfluidic separation devices
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United States of America Patent
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-
Dec 26, 2006
Grant Date -
Jan 13, 2005
app pub date -
Aug 10, 2004
filing date -
Feb 13, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A multi-layer microfluidic separation device comprises a polymeric membrane frit that may be securely bonded within the device and minimizes lateral wicking. Stationary phase material having an average particle size is retained by a frit having an average pore size that is smaller than the average particle size. In one embodiment, a secure bond is ensured by treating the polymer to match its surface energy to that of the materials to which it is bound. Treatments include plasma treatment, irradiation and the application of acids.
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