Aminoketone asymmetric reductase and nucleic acid thereof

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United States of America Patent

PATENT NO 7166452
APP PUB NO 20040247583A1
SERIAL NO

10469682

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Abstract

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A protein, which is an aminoketone asymmetric reductase, having an effect of producing d-pseudoephedrine by acting on 1-2-methylaminopropiophenone, and having the following physiochemical properties: substrate: 1-2-methylaminopropiophenone optimum pH: pH 8.1 optimum temperature: 55.degree. C. coenzyme: NADP molecular weight: about 28500 Da homotetramer and a nucleic acid coding the protein.

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Patent Owner(s)

Patent OwnerAddress
DAIICHI FINE CHEMICAL CO LTDTOYAMA PREFECTURE JAPAN TOYAMA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kataoka, Michihiko Kyoto, JP 10 55
Kita, Shinji Takaoka, JP 20 398
Morikawa, Tadanori Takaoka, JP 7 22
Sakamoto, Keiji Takaoka, JP 111 1462
Shimizu, Sakayu Kyoto, JP 86 533
Tsuzaki, Kazuya Takaoka, JP 3 1

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