Synthetic heparin-binding growth factor analogs
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United States of America Patent
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Jan 23, 2007
Grant Date -
Feb 26, 2004
app pub date -
Aug 20, 2002
filing date -
Aug 20, 2002
priority date (Note) -
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Abstract
The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.
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