US Patent No: 7,167,750

Number of patents in Portfolio can not be more than 2000

Obesity treatment with electrically induced vagal down regulation

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ALSO PUBLISHED AS: 20040167583
ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is innervated by at least a vagal trunk. An electrode is disposed on the carrier and positioned at the vagal trunk. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ENTEROMEDICS INC.ST PAUL, MN25

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Conrad, Timothy R Eden Prairie, MN 110 1718
Knudson, Mark B Shoreview, MN 153 5890
Tweden, Katherine S Mahtomedi, MN 70 1687
Wilson, Richard R Seattle, WA 67 803

Cited Art

Patent Info (Count) # Cites Year
 
ENTEROMEDICS INC. (5)
2004/0172,085 Nerve stimulation and conduction block therapy 73 2003
2004/0176,812 Enteric rhythm management 80 2003
2005/0070,970 Movement disorder stimulation with neural block 38 2004
2005/0070,974 Obesity and eating disorder stimulation treatment with neural block 46 2004
2005/0038,484 Controlled vagal blockage therapy 71 2004
 
MEDTRONIC, INC. (5)
6,097,984 System and method of stimulation for treating gastro-esophageal reflux disease 131 1998
6,853,862 Gastroelectric stimulation for influencing pancreatic secretions 82 2000
6,928,320 Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated 92 2001
2004/0236,381 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 38 2003
2004/0236,382 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 38 2003
 
NEURO AND CARDIAC TECHNOLOGIES, LLC (5)
2003/0212,440 Method and system for modulating the vagus nerve (10th cranial nerve) using modulated electrical pulses with an inductively coupled stimulation system 98 2002
7,076,307 Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders 47 2004
2005/0137,644 Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders 39 2005
2005/0143,787 Method and system for providing electrical pulses for neuromodulation of vagus nerve(s), using rechargeable implanted pulse generator 92 2005
2005/0149,146 Method and system to provide therapy for obesity and other medical disorders, by providing electrical pules to symapthetic nerves or vagal nerve(s) with rechargeable implanted pulse generator 75 2005
 
CYBERONICS, INC. (3)
5,231,988 Treatment of endocrine disorders by nerve stimulation 267 1991
5,263,480 Treatment of eating disorders by nerve stimulation 268 1992
5,540,730 Treatment of motility disorders by nerve stimulation 347 1995
 
BIOCONTROL MEDICAL LTD. (2)
6,684,105 Treatment of disorders by unidirectional nerve stimulation 159 2001
2003/0045,909 Selective nerve fiber stimulation for treating heart conditions 167 2002
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (2)
2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders 2001
2006/0036,293 Methods for treating gastrointestinal disorders 46 2005
 
ADVANCED NEUROMODULATION SYSTEMS, INC. (1)
2003/0181,958 Electric modulation of sympathetic nervous system 113 2002
 
ALLERGAN, INC. (1)
2001/0012,828 Intraspinal botulinum toxin for treating pain 16 2001
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
6,826,428 Gastrointestinal electrical stimulation 123 2002
 
CASE WESTERN RESERVE UNIVERSITY (1)
5,199,430 Micturitional assist device 96 1991
 
CEDARS-SINAI MEDICAL CENTER (1)
6,558,708 Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia 43 2000
 
CEREBRAL STIMULATION, INC. (1)
5,514,175 Auricular electrical stimulator 72 1994
 
DILORENZO BIOMEDICAL, LLC (1)
2003/0018,367 Method and apparatus for neuromodulation and phsyiologic modulation for the treatment of metabolic and neuropsychiatric disease 117 2002
 
FLINT HILLS SCIENTIFIC, L.L.C. (1)
6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures 243 1999
 
LEPTOS BIODMEDICAL, INC. (1)
2003/0181,959 Wireless electric modulation of sympathetic nervous system 59 2002
 
MEDTRONIC TRANSNEURONIX, INC. (1)
6,895,278 Gastric stimulator apparatus and method for use 80 1999
 
METACURE LIMITED (1)
6,993,391 Acute and chronic electrical signal therapy for obesity 29 2003
 
PALO ALTO INVESTORS (1)
2005/0143,378 Treatment of conditions through pharmacological modulation of the autonomic nervous system 16 2003
 
SEPRACOR INC. (1)
6,369,079 Methods for treating irritable bowel syndrome using optically pure (+) norcisapride 19 2000
 
TECHNOLOGIES INTERNATIONAL INC., UNIVERSITY (1)
6,449,511 Gastrointestinal electrical stimulator having a variable electrical stimulus 79 2000
 
TRANSNEURONIX, INC. (1)
5,423,872 Process and device for treating obesity and syndromes related to motor disorders of the stomach of a patient 237 1993

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
CYBERONICS, INC. (16)
7,899,540 Noninvasively adjustable gastric band 1 2005
7,835,796 Weight loss method and device 0 2005
7,996,079 Input response override for an implantable medical device 0 2006
7,657,310 Treatment of reproductive endocrine disorders by vagus nerve stimulation 2 2006
7,962,220 Compensation reduction in tissue stimulation therapy 2 2006
7,869,885 Threshold optimization for tissue stimulation therapy 2 2006
7,869,867 Implantable neurostimulator with refractory stimulation 0 2006
7,706,875 Modulation of drug effects by vagus nerve stimulation 1 2007
7,904,175 Trans-esophageal vagus nerve stimulation 2 2007
7,869,884 Non-surgical device and methods for trans-esophageal vagus nerve stimulation 0 2007
7,974,701 Dosing limitation for an implantable medical device 2 2007
7,962,214 Non-surgical device and methods for trans-esophageal vagus nerve stimulation 1 2007
8,260,426 Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device 0 2008
8,204,603 Blocking exogenous action potentials by an implantable medical device 0 2008
8,239,028 Use of cardiac parameters in methods and systems for treating a chronic medical condition 0 2009
7,901,613 Vacuum mandrel for use in fabricating an implantable electrode 0 2010
 
ENTEROMEDICS INC. (16)
7,844,338 High frequency obesity treatment 4 2004
7,613,515 High frequency vagal blockage therapy 18 2005
7,822,486 Custom sized neural electrodes 9 2005
7,672,727 Neural electrode treatment 5 2005
7,986,995 Bulimia treatment 2 2007
7,720,540 Pancreatitis treatment 6 2007
7,693,577 Irritable bowel syndrome treatment 6 2007
7,630,769 GI inflammatory disease treatment 8 2007
8,068,918 Remote monitoring and control of implantable devices 1 2007
7,729,771 Nerve stimulation and blocking for treatment of gastrointestinal disorders 6 2007
8,140,167 Implantable therapy system with external component having multiple operating modes 1 2007
8,326,426 Implantable device with heat storage 0 2009
8,103,349 Neural electrode treatment 2 2009
8,010,204 Nerve blocking for treatment of gastrointestinal disorders 1 2010
8,046,085 Controlled vagal blockage therapy 1 2010
8,369,952 Bulimia treatment 0 2011
 
NEVRO CORPORATION (9)
8,255,057 Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions 0 2009
8,423,147 Devices for controlling high frequency spinal cord modulation for inhibiting pain, and associated systems and methods, including simplified controllers 0 2011
8,209,021 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2011
8,170,675 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2011
8,396,559 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2012
8,428,748 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2012
8,359,102 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2012
8,359,103 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2012
8,355,792 Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods 0 2012
 
VIBRYNT, INC., A DELAWARE CORPORATION (9)
8,070,768 Devices and methods for treatment of obesity 0 2006
8,398,668 Devices and methods for treatment of obesity 0 2007
8,342,183 Devices and methods for treatment of obesity 0 2007
8,356,605 Devices and methods for treatment of obesity 0 2008
8,353,925 Devices and methods for treatment of obesity 0 2008
8,001,974 Devices and methods for treatment of obesity 3 2008
8,360,069 Devices and methods for treatment of obesity 0 2008
7,976,554 Devices, tools and methods for performing minimally invasive abdominal surgical procedures 1 2009
8,382,775 Methods, instruments and devices for extragastric reduction of stomach volume 0 2012
 
ELECTROCORE LLC (6)
7,725,188 Electrical stimulation treatment of hypotension 1 2006
8,209,034 Methods and apparatus for electrical stimulation treatment using esophageal balloon and electrode 0 2008
8,401,650 Methods and apparatus for electrical treatment using balloon and electrode 0 2009
7,869,879 Electrical stimulation treatment of hypotension 1 2009
8,041,428 Electrical stimulation treatment of hypotension 1 2009
8,233,988 Electrical stimulation treatment of hypotension 0 2011
 
CATHOLIC HEALTHCARE WEST (3)
8,219,188 Synchronization of vagus nerve stimulation with the cardiac cycle of a patient 0 2007
8,150,508 Vagus nerve stimulation method 0 2007
8,280,505 Vagus nerve stimulation method 0 2009
 
FLINT HILLS SCIENTIFIC, L.L.C. (3)
8,417,344 Dynamic cranial nerve stimulation based on brain state determination from cardiac data 0 2008
8,337,404 Detecting, quantifying, and/or classifying seizures using multimodal data 0 2010
8,382,667 Detecting, quantifying, and/or classifying seizures using multimodal data 0 2011
 
GERTNER, MICHAEL (3)
7,946,976 Methods and devices for the surgical creation of satiety and biofeedback pathways 0 2005
8,070,673 Devices and methods to treat a patient 0 2006
7,963,907 Closed loop gastric restriction devices and methods 1 2010
 
DAEMEN COLLEGE (2)
7,837,719 Electrical stimulation unit and waterbath system 6 2003
7,744,639 Electrical stimulation unit and waterbath system 0 2003
 
BARONOVA, INC. (1)
8,048,169 Pyloric valve obstructing devices and methods 0 2004
 
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (1)
8,192,455 Compressive device for percutaneous treatment of obesity 0 2004
 
INTRAPACE, INC. (1)
7,676,270 Radially expandable gastrointestinal stimulation device 0 2005
 
SETPOINT MEDICAL CORPORATION (1)
8,412,338 Devices and methods for optimizing electrode placement for anti-inflamatory stimulation 0 2009
 
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (1)
8,391,970 Devices and methods for inhibiting granulocyte activation by neural stimulation 0 2008
 
VIBSYNT, INC. (1)
8,187,297 Devices and methods for treatment of obesity 0 2007

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Jul 23, 2014
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jul 23, 2018
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00