Device for determining a glucose concentration in a tissue fluid

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United States of America Patent

PATENT NO 7169600
SERIAL NO

10782290

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.

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Patent Owner(s)

Patent OwnerAddress
ROCHE DIAGNOSTICS GMBH68305 MANNHEIM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fussgaenger, Rolf Blaustein-Weidach, DE 2 400
Gessler, Ralf Baienfurt, DE 4 661
Hoss, Udo Sherman Oaks, CA 213 10535
Pfleiderer, Hans-Joerg Ulm, DE 27 867
Zieten, Hans-Ulrich Illerrieden, DE 2 400

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