Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
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United States of America Patent
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Jan 30, 2007
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N/A
app pub date -
Jun 19, 2000
filing date -
Jun 19, 1999
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Abstract
The present invention relates generally to hydrolyzable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates, and to methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG, and oleic acid can be orally administered.
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