Nucleic acid formulations for gene delivery and methods of use
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United States of America Patent
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Feb 6, 2007
Grant Date -
Jun 12, 2003
app pub date -
Sep 3, 2002
filing date -
Mar 3, 2000
priority date (Note) -
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Abstract
A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes aniionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
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