Electroactive microspheres and methods
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United States of America Patent
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Feb 13, 2007
Grant Date -
Mar 25, 2004
app pub date -
Sep 18, 2003
filing date -
Sep 20, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair to be detected is bound, directly or through one or more intermediates, to the microsphere. Multiple specific binding pair members may be detected by use of electrochemically distinguishable electroactive markers. Microspheres with incorporated electroactive markers may include one or more functional groups for binding members of specific binding pairs, and are preferably insoluble in aqueous solvents but soluble in selected organic solvents.
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