Conformationally restricted polyamine analogs as disease therapies
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United States of America Patent
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Mar 6, 2007
Grant Date -
Nov 25, 2004
app pub date -
Jun 21, 2004
filing date -
Apr 30, 1999
priority date (Note) -
Expired
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Abstract
Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.
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