Human antibodies as detection reagents
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United States of America Patent
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Mar 13, 2007
Grant Date -
Sep 4, 2003
app pub date -
Dec 6, 2000
filing date -
Dec 6, 1999
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The invention provides in vitro methods of detection using human antibodies. The methods are particularly useful for analyzing human samples containing HAMA or heterophilic antibodies. A human antibody can bind to an analyte in such samples without binding to HAMA or heterophilic antibodies present in the samples. The methods can be effected using a sandwich format among others.
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