Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof
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United States of America Patent
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Mar 13, 2007
Grant Date -
Apr 22, 2004
app pub date -
Jun 13, 2003
filing date -
Jun 14, 2002
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Abstract
The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, and to host cells in which such encoding polynucleotides can be advantageously expressed.
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