Low coherence interferometry for detecting and characterizing plaques
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United States of America Patent
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Mar 13, 2007
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N/A
app pub date -
Jan 21, 2005
filing date -
May 14, 2004
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Abstract
A method and system for determining a characteristic of a biological sample including directing light at the biological sample and receiving that light; directing the light at a reference reflecting device and receiving that light; adjusting an effective light path length to facilitate an interference of the light reflected from the biological sample corresponding to a first depth and the light reflected from the reference reflecting device; and detecting the broadband light resulting from the interference, to provide an interference signal. The method also includes: determining a first phase associated with the interference signal corresponding to the first depth; varying the effective light path length to define a second depth; determining a second phase associated with the interference signal corresponding to the second depth; and determining the characteristic of the biological sample from the phases.
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