Process for the synthesis of oligomeric compounds

United States of America Patent

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Apr 3, 2007
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Jun 23, 2005
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Sep 14, 2004
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Feb 4, 1999

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Abstract

Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.

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Patent Owner	Address
IONIS PHARMACEUTICALS INC	2855 GAZELLE COURT CARLSBAD CA 90210

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C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....

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Inventor Name	Address	# of filed Patents	Total Citations
Capaldi, Daniel C	San Diego, CA	25	390
Cole, Douglas L	San Diego, CA	192	1362
Guzaev, Andrei	Carlsbad, CA	12	124
Krotz, Achim	San Diego, CA	11	395
Manoharan, Muthiah	Carlsbad, CA	491	18658
Ravikumar, Vasulinga T	Carlsbad, CA	39	625

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Process for the synthesis of oligomeric compounds

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United States of America Patent

10940360

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PATENT NO	7199236
APP PUB NO	20050137391A1
SERIAL NO	10940360
DOCKET NO

US Family Size	Non-US Coverage
Patent Longevity	Forward Citations

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
April 03, 2007	US,7199236,B2 US7199236B2	GRANTED PATENT AS SECOND PUBLICATION
June 23, 2005	US,20050137391,A1 US20050137391A1	FIRST PUBLISHED PATENT APPLICATION

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10940360

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