Method and composition for the treatment of lung surfactant deficiency or dysfunction

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7201167
APP PUB NO 20050229926A1
SERIAL NO

11080279

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A method of treating a disease involving surfactant deficiency or dysfunction in a patient's lungs is disclosed comprising the steps of providing a liquid lung surfactant composition; aerosolizing the lung surfactant composition with a vibrating aperture-type aerosol generator to form a surfactant aerosol; and introducing the surfactant aerosol into the gas flow within a circuit of a pressure-assisted breathing system coupled to the patient's respiratory system, whereby a therapeutically effective amount of said surfactant is delivered to the patient's lungs. Apparatus is also disclosed that increases the efficiency of delivery of aerosolized medicaments such as aerosolized lung surfactant.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
NOVARTIS AGBASEL2794

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fink, James San Mateo, CA 8 542
Ivri, Yehuda Newport Beach, CA 47 1982

Cited Art Landscape

Patent Info (Count) # Cites Year
 
MINNESOTA MINING AND MANUFACTURING COMPANY (6)
4819834 Apparatus and methods for delivering a predetermined amount of a pressurized fluid 110 1986
5115803 Aerosol actuator providing increased respirable fraction 68 1990
5347998 Breath actuated inhaler having an electromechanical priming mechanism 122 1992
5487378 Inhaler 205 1993
5477992 Metered-dose aerosol valves 46 1994
5515841 Inhaler 81 1994
 
Other [Check patent profile for assignment information] (29)
4368850 Dry aerosol generator 59 1980
4299784 Apparatus for producing an aerosol 68 1980
* 4502481 Device for manually ventilating a patient 29 1983
4628890 Fuel atomizer 68 1984
4826080 Fuel injection device for internal combustion engines 61 1986
5022587 Battery powered nebulizer 48 1989
5007419 Inhaler device 86 1989
5140740 Method of retrofitting a stator end winding 44 1990
5062419 Nebulizer with valved "T" assembly 53 1991
5186164 Mist inhaler 133 1991
5297734 Ultrasonic vibrating device 86 1991
5372126 Pulmonary sampling chamber 42 1992
5313955 Pulmonary flow head 42 1992
5388571 Positive-pressure ventilator system with controlled access for nebulizer component servicing 224 1992
5396883 Nebulizer valve assembly for use in a ventilation circuit 38 1993
5437267 Device for delivering aerosol to the nasal membranes and method of use 181 1993
5485850 Monitor of low pressure intervals with control capabilities 65 1993
5897008 Ampule with offset longitudinal passage 35 1993
5415161 Intermittant demand aerosol control device 80 1993
5752502 General purpose aerosol inhalation apparatus 62 1993
5588166 Medical attachment device 90 1995
5533497 Sidestream aerosol generator and method in variable positions 83 1995
5657926 Ultrasonic atomizing device 75 1995
5878900 Plastic bottle with two separation areas 35 1996
6106504 Drip chamber for medical fluid delivery system 33 1998
6182662 Intravenous transport/support device 51 1998
6328030 Nebulizer for ventilation system 48 1999
* 6860268 Pediatric ventilation mask and headgear system 73 2002
2005/0220,763 Method of treating idiopathic pulmonary fibrosis with aerosolized IFN-gamma 12 2005
 
SHERWOOD SERVICES AG (2)
5357946 Ventilator manifold with accessory access port and adaptors therefore 198 1993
5445141 Respiratory support system 55 1994
 
ELKEM AS (1)
5654460 Method for production of aklylhalosilanes 44 1995
 
1263152 ONTARIO INC. (1)
6358058 Aerosol dispensing inhaler training device 61 1998
 
SAMSUNG ELECTRONICS CO., LTD. (1)
2003/0193,657 Range finder device and camera 43 2003
 
IBM INFORMATION PRODUCTS CORPORATION, 55 RAILROAD AVENUE, GREENWICH, CT 06830 A CORP OF DE (1)
4475113 Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids 72 1983
 
BSH BOSCH UND SIEMENS HAUSGERÄTE GMBH (2)
4334531 Inhalator 101 1980
4301093 Atomizer for liquid 94 1980
 
VOTRAN MEDICAL TECHNOLOGY, INC., A CORP. OF CA (1)
5322057 Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use 249 1991
 
Nisshin Kasei Kabushiki Kaisha (1)
4428802 Palladium-nickel alloy electroplating and solutions therefor 31 1981
 
Kraftwerk Union Aktiengesellschaft (1)
4431136 Slit nozzle and fast-acting shutoff valve 56 1981
 
HEALX CORPORATION (1)
5227168 Method of treating a wound 62 1992
 
AEROGEN, INC. (1)
6546927 Methods and apparatus for controlling piezoelectric vibration 59 2001
 
KOS LIFE SCIENCES, INC. (1)
6116234 Metered dose inhaler agitator 38 1999
 
Habley Medical Technology Corporation (1)
5435282 Nebulizer 93 1994
 
ISONIX LLC (1)
5516043 Ultrasonic atomizing device 109 1994
 
MEZZANINE OPPORTUNITIES LLC, AS AGENT (1)
5086765 Nebulizer 71 1990
 
Instrumentation Corp. (1)
6530370 Nebulizer apparatus 64 1999
 
WESTROCK DISPENSING SYSTEMS, INC. (1)
5839617 Pump dispenser 30 1997
 
ETHICON, INC. (1)
5714551 High strength, melt processable, lactide-rich, poly (lactide-co-p-dioxanone) copolymers 57 1996
 
Med-Safe Systems, Inc. (1)
5230496 Pole mounting clamp 86 1991
 
SENSORMEDICS CORPORATION (2)
6581595 Positive airway pressure device with indirect calorimetry system 49 2000
2002/0078,958 Infant CPAP system with airway pressure control 30 2000
 
GLAXO WELLCOME INC. (1)
6186141 Unit dose dispensing device 61 1999
 
Piezo Electric Products, Inc. (2)
4702418 Aerosol dispenser 127 1985
4753579 Ultrasonic resonant device 77 1986
 
GLAXO WELLCOME AUSTRALIA LTD. (1)
5819730 Device for administering pharmaceutical substances 43 1996
 
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (1)
6000396 Hybrid microprocessor controlled ventilator unit 79 1995
 
Toa Nenryo Kogyo Kabushiki Kaisha (1)
4799622 Ultrasonic atomizing apparatus 69 1987
 
ATOTECH USA, INC. (1)
6045874 Fluid delivery method 29 1998
 
PROFILE DRUG DELIVERY LIMITED (1)
5842468 Dosimetric spacer for calculating dosage administered 53 1997
 
RIC INVESTMENTS, LLC. (3)
* 5537997 Sleep apnea treatment apparatus and passive humidifier for use therewith 145 1995
* 5694923 Pressure control in a blower-based ventilator 70 1996
* 6467477 Breath-based control of a therapeutic treatment 63 2000
 
HEWLETT-PACKARD COMPANY (2)
4336544 Method and apparatus for drop-on-demand ink jet printing 72 1980
5016024 Integral ink jet print head 62 1990
 
RIC INVESTMENTS, INC. (1)
* 5148802 Method and apparatus for maintaining airway patency to treat sleep apnea and other disorders 329 1989
 
L'OREAL (2)
5529055 Piezoelectric nebulizing apparatus 62 1994
5692644 Container for storing at least two products, mixing these products, and dispensing the mixture thus obtained 83 1995
 
HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (8)
5426458 Poly-p-xylylene films as an orifice plate coating 84 1993
5560837 Method of making ink-jet component 86 1994
6123413 Reduced spray inkjet printhead orifice 49 1997
6045215 High durability ink cartridge printhead and method for making the same 46 1997
6145963 Reduced size printhead for an inkjet printer 32 1997
6155676 High-durability rhodium-containing ink cartridge printhead and method for making the same 55 1997
6254219 Inkjet printhead orifice plate having related orifices 45 1998
6146915 Reduced size printhead for an inkjet printer 41 1999
 
Swema Instrument Aktiebolag (1)
4843445 Integrated semiconductor circuit and method for producing it, and use of such a circuit for providing a flow meter 41 1987
 
U.S. PHILIPS CORPORATION (1)
4828886 Method of applying small drop-shaped quantities of melted solder from a nozzle to surfaces to be wetted and device for carrying out the method 87 1987
 
Confab Guy Lamarre Inc. (1)
5213860 Plastic ampul 40 1990
 
BOEHRINGER INGELHEIM INTERNATIONAL GMBH (1)
5497944 Atomising devices and methods 160 1992
 
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (1)
6060128 Method of producing thin film and nanoparticle deposits using charges of alternating polarity 46 1999
 
TSI INCORPORATED (1)
6158431 Portable systems and methods for delivery of therapeutic material to the pulmonary system 249 1998
 
SENSITRON, INC. (2)
5157372 Flexible potentiometer 75 1990
5309135 Flexible potentiometer in a horn control system 82 1993
 
WARNER-LAMBERT COMPANY (1)
4268460 Nebulizer 151 1980
 
RICOH COMPANY, LTD. (1)
4591883 Ink-jet printer head 57 1985
 
SUN MICROSYSTEMS, INC. (1)
5129579 Vacuum attachment for electronic flux nozzle 34 1990
 
Berkshire Research Partners (1)
* 4340044 Volume ventilator 102 1980
 
STAMFORD DEVICES LIMITED (3)
6014970 Methods and apparatus for storing chemical compounds in a portable inhaler 140 1998
6205999 Methods and apparatus for storing chemical compounds in a portable inhaler 74 1998
6814071 Methods and apparatus for aerosolizing a substance 47 2002
 
DEVILBISS HEALTH CARE, INC. (1)
5170782 Medicament nebulizer with improved aerosol chamber 99 1991
 
Material Engineering Technology Laboratory, Incorporated (1)
4872553 Medical fluid-filled plastic container and methods of making same 57 1987
 
Mountain Medical Equipment, Inc. (1)
4976259 Ultrasonic nebulizer 101 1988
 
The United States of America as represented by the Secretary of the Navy (1)
5474059 Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient 87 1995
 
BESPAK PLC (3)
5348189 Air purge pump dispenser 66 1993
5350116 Dispensing apparatus 33 1993
5458289 Liquid dispensing apparatus with reduced clogging 46 1994
 
Dynamics Research Corporation (1)
4954225 Method for making nozzle plates 40 1990
 
INFO TRUST, INC. (1)
2005/0197,169 Battery pack having a dual-type smart card interface 35 2005
 
SOCIETE FRANCAISE D'AEROSOLS ET DE BOUCHAGE A FRENCH COMPANY (1)
5169029 Mixing dispenser and method of using same 123 1991
 
THE TECHNOLOGY PARTNERSHIP PLC (2)
5518179 Fluid droplets production apparatus and method 141 1994
6394363 Liquid projection apparatus 48 2000
 
SEIKO EPSON CORPORATION (2)
5063396 Droplets jetting device 67 1990
5670999 Ink jet print head having members with different coefficients of thermal expansion 57 1996
 
SURMODICS, INC. (14)
4722906 Binding reagents and methods 226 1982
5073484 Quantitative analysis apparatus and method 184 1983
4826759 Field assay for ligands 163 1984
4979959 Biocompatible coating for solid surfaces 339 1989
5002582 Preparation of polymeric surfaces via covalently attaching polymers 271 1989
5258041 Method of biomolecule attachment to hydrophobic surfaces 129 1991
5217492 Biomolecule attachment to hydrophobic surfaces 173 1991
5263992 Biocompatible device with covalently bonded biocompatible agent 218 1991
5654162 Chemical analysis apparatus and method 106 1992
5414075 Restrained multifunctional reagent for surface modification 141 1992
5512329 Substrate surface preparation 110 1993
5637460 Restrained multifunctional reagent for surface modification 103 1994
5563056 Preparation of crosslinked matrices containing covalently immobilized chemical species and unbound releasable chemical species 167 1995
5714360 Photoactivatable water soluble cross-linking agents containing an onium group 133 1995
 
XEROX CORPORATION (5)
4374707 Orifice plate for ink jet printing machines 60 1981
4678680 Corrosion resistant aperture plate for ink jet printers 45 1986
4658269 Ink jet printer with integral electrohydrodynamic electrodes and nozzle plate 69 1986
5685491 Electroformed multilayer spray director and a process for the preparation thereof 76 1995
6139674 Method of making an ink jet printhead filter by laser ablation 50 1997
 
KANFER, JOSEPH S. (1)
6216916 Compact fluid pump 93 1999
 
APTAR FRANCE SAS (2)
6196219 Liquid droplet spray device for an inhaler suitable for respiratory therapies 103 1998
6405934 Optimized liquid droplet spray device for an inhaler suitable for respiratory therapies 60 1999
 
PONWELL ENTERPRISES LIMITED, A BRITISH VIRGIN ISLANDS COMPANY, C/O BYRNE TRUST COMPANY LIMITED. (1)
6196218 Piezo inhaler 198 1999
 
HAHN, GARY S. (1)
5893515 Mist generator 58 1994
 
PESCADERO BEACH HOLDINGS CORPORATION (2)
5122116 Closed drug delivery system 95 1990
6007518 Fluid delivery device with conformable ullage and fill assembly 43 1998
 
CORNING INCORPORATED (1)
4871489 Spherical particles having narrow size distribution made by ultrasonic vibration 89 1988
 
ETELA-HAMEEN KEUHKOVAMMAYHDISTYS R.Y. (1)
* 5063922 Ultrasonic atomizer 262 1989
 
BATTELLE MEMORIAL INSTITUTE (5)
5115971 Nebulizer device 59 1988
5511726 Nebulizer device 186 1993
5915377 Dispensing device producing multiple comminutions of opposing polarities 88 1997
6105877 Dispensing device 85 1997
6318640 Dispensing device 90 2000
 
SALTER LABS (2)
* 5584285 Breathing circuit apparatus for a nebulizer 117 1995
* 6904906 Nebulizer mouthpiece and accessories 35 2003
 
I.P.S. INDUSTRIE DES POUDRES SPHERIQUES S.A. (1)
5198157 Ultrasonic device for the continuous production of particles 72 1991
 
IMRA EUROPE SA (1)
5836515 High efficiency spraying device, in particular for spraying water in the form of micro-droplets 36 1997
 
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (1)
5744515 Method and implantable article for promoting endothelialization 215 1996
 
UNIVERSITY OF AUCKLAND (1)
4677975 Method of dispensing and/or a dispenser 384 1985
 
CATALENT USA WOODSTOCK, INC. (2)
D392184 Vial with a frangible closure 58 1996
6068148 Hermetically sealed container including a nozzle with a sealing bead 43 1998
 
Thayer Medical Corporation (1)
* 4951661 Quick-connect adapter valve for connecting nebulizer and fluid ventilator hose 75 1989
 
XETEL CORPORATION (1)
5452711 Small form factor atomizer 64 1993
 
TTP GROUP PLC (1)
5823428 Liquid spray apparatus and method 62 1996
 
LG ELECTRONICS INC. (1)
2005/0188,472 Washer damper thereof, and control method thereof 17 2005
 
BECTON, DICKINSON AND COMPANY (4)
4613326 Two-component medication syringe assembly 145 1985
D312209 Dispensing vial or the like 53 1988
5601077 Nasal syringe sprayer with removable dose limiting structure 80 1991
5489266 Syringe assembly and method for lyophilizing and reconstituting injectable medication 112 1994
 
FREEDOM MULTIMEDIA LLC (1)
5086785 Angular displacement sensors 167 1989
 
Roberts; Josephine A. (1)
4805609 Pressurized ventilation system for patients 79 1987
 
PNC BANK, NATIONAL ASSOCIATION (1)
5609798 High output PSL aerosol generator 62 1995
 
STELLA KG WERNER DEUSSEN, A CORP. OF WEST GERMANY (1)
4926915 Ampul 50 1988
 
Boehringer Ingelheim GmbH (1)
4261512 Inhalation aerosol spray device 50 1980
 
ING. ERICH PFEIFFER GMBH (1)
5964417 Dispenser for discharging media 45 1997
 
CAREFUSION 2200, INC. (1)
5579757 Anti-siphon flow restricter for a nebulizer 58 1994
 
INJET DIGITAL AEROSOLS LIMITED (2)
5894841 Dispenser 340 1995
6443146 Piezo inhaler 118 2000
 
imaging Technology international Corp. (1)
5790151 Ink jet printhead and method of making 203 1996
 
ALLIANCE PHARMACEUTICAL CORP. (1)
5788665 Apparatus for pulmonary therapy 49 1995
 
Ing. C. Olivetti & C., S.p.A. (1)
4546361 Ink jet printing method and device 64 1983
 
ARADIGM CORPORATION (11)
5392768 Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval 151 1993
5709202 Intrapulmonary delivery of aerosolized formulations 112 1993
5419315 Intrapulmonary delivery of hormones 69 1994
5542410 Delivery of aeerosol medications for inspiration 78 1994
5718222 Disposable package for use in aerosolized delivery of drugs 119 1995
5724957 Intrapulmonary delivery of narcotics 191 1995
5960792 Device for aerosolized delivery of peptide drugs 194 1995
5660166 Systems for the intrapulmonary delivery of aerosolized aqueous formulations 95 1996
6012450 Intrapulmonary delivery of hematopoietic drug 153 1996
5755218 Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval 165 1996
6688304 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 13 2001
 
Hydronautics, Incorporated (1)
4681264 Enhancing liquid jet erosion 81 1984
 
KABI PHARMACIA AB (1)
4968299 Method and device for injection 143 1988
 
CONSORT MEDICAL PLC (6)
5152456 Dispensing apparatus having a perforate outlet member and a vibrating device 130 1990
5261601 Liquid dispensing apparatus having a vibrating perforate membrane 132 1992
5664706 Apparatus for dispensing liquid in aerosol spray form 35 1995
6062212 Dispensing apparatus 71 1995
5653227 Atomizing dispenser 49 1995
6047818 Dual component dispensing apparatus 37 1997
 
Mobacc B.V. (1)
4957239 Spray head for an aerosol container 35 1989
 
SPRAYFORMING DEVELOPMENTS LIMITED (1)
5635096 Vibrating ring motor for feeding particulate substances 31 1995
 
AGILENT TECHNOLOGIES, INC. (1)
6037587 Chemical ionization source for mass spectrometry 38 1997
 
R. J. REYNOLDS TOBACCO COMPANY (1)
4922901 Drug delivery articles utilizing electrical energy 267 1988
 
COLUMBIA LABORATORIES, INC. (1)
D375352 Dispensing vial for feminine hygiene products 54 1994
 
Hudson Oxygen Therapy Sales Company (1)
4512341 Nebulizer with capillary feed 76 1982
 
IMAGING SOLUTIONS, INC. (1)
4593291 Method for operating an ink jet device to obtain high resolution printing 55 1984
 
SANDEN CORPORATION (1)
5449502 Sterilizing apparatus utilizing ultrasonic vibration 36 1994
 
NGK INSULATORS, LTD. (1)
6443366 Liquid-drop discharge device 31 2000
 
System Assistance Medical (1)
5865171 Nebulizer with pressure sensor 75 1997
 
WELLS FARGO BANK, NATIONAL ASSOCIATION (1)
5479920 Breath actuated medicinal aerosol delivery apparatus 314 1994
 
NOVARTIS AG (3)
2002/0011,247 Methods and apparatus for storing chemical compounds in a portable inhaler 34 2000
2005/0011,514 Nebuliser for the production of aerosolized medication 45 2004
2005/0139,211 Introducing aerosol into a ventilator 66 2004
 
ARZNEIMITTEL GMBH APOTHEKER VETTER & CO. RAVENSBURG (2)
5080649 Dual-compartment hypodermic syringe 129 1990
5320603 Hypodermic syringe for lyophilized medicament 114 1992
 
MEDEX, INC. (3)
5186166 Powder nebulizer apparatus and method of nebulization 88 1992
5355872 Low flow rate nebulizer apparatus and method of nebulization 105 1992
5829723 Medical device mounting structure 55 1995
 
NEKTAR THERAPEUTICS (1)
2003/0150,445 Apparatus and methods for delivery of medicament to a respiratory system 32 2002
 
MEASUREMENT SPECIALTIES, INC. (1)
5201322 Device for detecting air flow through a passageway 51 1990
 
Lechler GmbH & Co. KG (1)
4796807 Ultrasonic atomizer for liquids 66 1988
 
NOVARTIS PHARMA AG (29)
5164740 High frequency printing mechanism 127 1991
5248087 Liquid droplet generator 65 1992
5458135 Method and device for delivering aerosolized medicaments 285 1992
6629646 Droplet ejector with oscillating tapered aperture 76 1993
5938117 Methods and apparatus for dispensing liquids as an atomized spray 132 1995
5654007 Methods and system for processing dispersible fine powders 135 1995
5586550 Apparatus and methods for the delivery of therapeutic liquids to the respiratory system 140 1995
5758637 Liquid dispensing apparatus and methods 222 1996
6085740 Liquid dispensing apparatus and methods 214 1998
6755189 Methods and apparatus for storing chemical compounds in a portable inhaler 39 1999
6540153 Methods and apparatus for dispensing liquids as an atomized spray 57 1999
6235177 Method for the construction of an aperture plate for dispensing liquid droplets 68 1999
6427682 Methods and apparatus for aerosolizing a substance 60 2000
6467476 Liquid dispensing apparatus and methods 65 2000
6543443 Methods and devices for nebulizing fluids 58 2000
6540154 Systems and methods for controlling fluid feed to an aerosol generator 62 2000
6550472 Devices and methods for nebulizing fluids using flow directors 66 2001
6782886 Metering pumps for an aerosolizer 35 2001
6554201 Insert molded aerosol generator and methods 50 2001
6732944 Base isolated nebulizing device and methods 44 2001
2002/0162,551 Cymbal-shaped actuator for a nebulizing element 33 2001
6615824 Apparatus and methods for the delivery of medicaments to the respiratory system 72 2001
2002/0134,374 Fluid filled ampoules and methods for their use in aerosolizers 31 2001
2002/0134,375 Fluid filled ampoules and methods for their use in aerosolizers 28 2001
2002/0121,274 Laminated electroformed aperture plate 34 2001
2002/0104,530 Piezoelectric polymer flow sensor and methods 35 2001
6851626 Methods and devices for nebulizing fluids 57 2002
6640804 Liquid dispensing apparatus and methods 64 2002
6845770 Systems and methods for clearing aerosols from the effective anatomic dead space 34 2003
 
DISETRONIC AG (1)
5515842 Inhalation device 147 1994
 
VENTAIRA PHARMACEUTICALS, INC. (1)
* 6705316 Pulmonary dosing system and method 71 2002
 
HITACHI, LTD. (1)
4865006 Liquid atomizer 52 1988
 
RESMED LIMITED (8)
5245995 Device and method for monitoring breathing during sleep, control of CPAP treatment, and preventing of apnea 446 1992
6705315 Device for monitoring breathing during sleep and ramped control of CPAP treatment 64 2001
2002/0036,601 CPAP apparatus for switching between operational modes of the CPAP apparatus and a controller and method for doing the same 18 2001
6840240 Control of supplied pressure in assisted ventilation 55 2002
6745770 Flow diverter for controlling the pressure and flow rate in a CPAP device 48 2002
6810876 Assisted ventilation to match patient respiratory need 92 2002
6817361 Administration of CPAP treatment pressure in presence of apnea 62 2002
6745768 Fault diagnosis in CPAP and NIPPV devices 45 2003
 
ZIVENA, INC. (1)
* 6269810 Pulmonary dosing system and method 80 1999
 
COCTOBER 10, 2003 RESTATEMENT OF TRUST A UNDER THE FORREST M. BIRD AND MARY P. BIRD REVOCABLE TRUST DATED JULY 29, 1983, THE (1)
5862802 Ventilator having an oscillatory inspiratory phase and method 108 1992
 
CARDINAL HEALTH 400, INC. (1)
D362390 Hermetically sealed vial 65 1994
 
AKAMAI TECHNOLOGIES, INC. (1)
2009/0132,648 CONTENT DELIVERY AND GLOBAL TRAFFIC MANAGEMENT NETWORK SYSTEM 77 2009
 
DELAVAN CORPORATION WEST DES MOINES (1)
4659014 Ultrasonic spray nozzle and method 99 1985
 
S.C. JOHNSON & SON, INC. (1)
6341732 Method and apparatus for maintaining control of liquid flow in a vibratory atomizing device 70 2000
 
WILLIAMS, GAYE (1)
5918637 Plates perforated with venturi-like orifices 35 1993
 
Jettek, Inc. (1)
6270473 Hypodermic jet injector and disposable ampule 41 1999
 
SILEX MICROSYSTEMS AB (1)
6055869 Lift force fluid flow sensor for measuring fluid flow velocities 32 1997
 
TMBC, INC. (1)
5383906 Nursing bottle with medication dispenser 51 1993
 
MICRODOSE THERAPEUTX, INC. (3)
6026809 Inhalation device 129 1996
6142146 Inhalation device 77 1998
6152130 Inhalation device with acoustic control 110 1998
 
CANON KABUSHIKI KAISHA (2)
4368476 Ink jet recording head 120 1980
5788819 Method for driving liquid, and method and apparatus for mixing and agitation employing the method 59 1997
 
WESTMED HOLDING COMPANY (1)
5080093 Intermittant signal actuated nebulizer 69 1990
 
TRANSPHARMA LTD. (1)
6328033 Powder inhaler 83 1999
 
LUCENT TECHNOLOGIES INC. (1)
5976344 Composition for electroplating palladium alloys and electroplating process using that composition 32 1997
 
SIEMENS AKTIENGESELLSCHAFT (8)
4539575 Recorder operating with liquid drops and comprising elongates piezoelectric transducers rigidly connected at both ends with a jet orifice plate 102 1984
4544933 Apparatus and method for ink droplet ejection for a printer 52 1984
4620201 Magnetic driver ink jet 48 1986
4888516 Piezoelectrically excitable resonance system 56 1988
4877989 Ultrasonic pocket atomizer 238 1989
5134993 Inhalator device, in particular a pocket inhalator 106 1989
5950619 Ultrasonic atomizer device with removable precision dosating unit 104 1997
5970974 Dosating unit for an ultrasonic atomizer device 158 1997
 
TOMTEC NV (1)
4679551 Device for performing therapeutic treatments 76 1985
 
TRUE GRAVITY ENTERPRISES, INC. (1)
5046627 Ampule 49 1990
 
Alexander Aloy (1)
6029666 Device for delivering a ventilation gas 24 1997
 
DRAGER MEDIZINTECHNIK GMBH (1)
6402046 Ultrasonic atomizer 53 2000
 
ARTE CORPORATION (1)
5665068 Dual chamber prefillable syringe 50 1995
 
SORIN BIOMEDICA S.P.A. (1)
5139016 Process and device for aerosol generation for pulmonary ventilation scintigraphy 70 1989
 
BAYER HEALTHCARE LLC (1)
6096011 Aseptic connector and fluid delivery system using such an aseptic connector 174 1998
 
DRAGERWERK AKTIENGESELLSCHAFT (1)
4693853 Anesthetic vaporizer 52 1986
 
BIO-METRIC SYSTEM, INC. (1)
4973493 Method of improving the biocompatibility of solid surfaces 397 1987
 
N.V. ORGANON (1)
4994043 Two compartment syringe 66 1988
 
TRACOR HYDRONAUTICS (2)
4389071 Enhancing liquid jet erosion 73 1980
4474251 Enhancing liquid jet erosion 77 1981
 
ROBERT BOSCH GMBH (1)
5319971 Measuring element for determining a flow rate of a flowing medium 31 1992
 
SURMODICS IVD, INC. (2)
5512474 Cell culture support containing a cell adhesion factor and a positively-charged molecule 96 1994
5707818 Device and method for simultaneously performing multiple competitive immunoassays 69 1994
 
The Kendall Company (1)
* 4852563 Multifunction connector for a breathing circuit 48 1987
 
COVIDIEN AG (1)
5342011 Fluid container attachment adaptor for an ambulatory fluid delivery system 32 1993
 
ALLERGAN, INC. (1)
5582330 Specific volume dispenser 107 1994
 
Key Pharmaceuticals, Inc. (1)
* 4484577 Drug delivery method and inhalation device therefor 191 1982
 
PHARMACIA AB (1)
5925019 Device for displacing a member in a container 35 1998
 
POLAROID CORPORATION (1)
4550325 Drop dispensing device 79 1984
 
MEDCARE MEDICAL GROUP, INC. (1)
6039696 Method and apparatus for sensing humidity in a patient with an artificial airway 75 1997
 
YAZAKI CORPORATION (1)
5342504 Palladium-nickel alloy plating solution 28 1993
 
True Products Sampling, Inc. (1)
D327008 Cosmetic sample container 42 1990
 
INSTRUMENTARIUM CORP. (1)
6769626 Device and method for detecting and controlling liquid supply to an apparatus discharging liquids 36 2000
 
FET Engineering, Inc. (1)
5632878 Method for manufacturing an electroforming mold 64 1995
 
Spruhventile GmbH (4)
5147073 Fluid pump dispenser for pharmaceutical use 53 1991
5217148 Pharmaceutical pump dispenser 38 1991
5303854 Pharmaceutical pump dispenser having hydraulically closed outlet port 32 1993
5279568 Pharmaceutical pump dispenser for fluid suspensions and fluid mixtures 32 1993
 
ALLEGIANCE CORPORATION (1)
4566452 Nebulizer 47 1984
 
SVEN-ERIK NILSSON (1)
4934358 Device for self-administration of physiologically active substances, with prevention of overdosing 139 1988
 
OMRON HEALTHCARE CO., LTD. (2)
6651650 Ultrasonic atomizer, ultrasonic inhaler and method of controlling same 50 1994
6273342 Atomizer 48 2000
 
TDK Electronics Co., Ltd. (1)
4474326 Ultrasonic atomizing device 76 1982
 
TDK CORPORATION (4)
4850534 Ultrasonic wave nebulizer 114 1988
5021701 Piezoelectric vibrator mounting system for a nebulizer 65 1989
5299739 Ultrasonic wave nebulizer 78 1992
5312281 Ultrasonic wave nebulizer 91 1992
 
BERG TECHNOLOGY, INC. (1)
4849303 Alloy coatings for electrical contacts 56 1988
 
BOETTNER, MELISSA (1)
4454877 Portable nebulizer or mist producing device 66 1981
 
Omron Tateisi Electronics Co. (2)
4793339 Ultrasonic atomizer and storage bottle and nozzle therefor 99 1988
4790479 Oscillating construction for an ultrasonic atomizer inhaler 111 1988
 
MICROLIN, L.C. (1)
5954268 Fluid delivery system 55 1998
 
MICROSPRAY DELTA S.P.A. (1)
5431155 Single-dose nasal dispenser for atomized liquid drugs 77 1993
 
WALLI, RICHARD A. (1)
4408719 Sonic liquid atomizer 59 1981
 
RESPIRATORY DELIVERY SYSTEMS, INC. (2)
5002048 Inhalation device utilizing two or more aerosol containers 99 1989
5664557 Releasably engageable coupling for an inhaler 66 1995
 
AT&T Bell Laboratories (2)
5024733 Palladium alloy electroplating process 58 1990
5180482 Thermal annealing of palladium alloys 43 1991
 
WELLDYNAMICS, B.V. (1)
6223746 Metered dose inhaler pump 84 1998
 
Automatic Liquid Packaging, Inc. (1)
4298045 Dispensing container with plural removable closure means unitary therewith 57 1980
 
Respirogenics Corporation (1)
5666946 Apparatus for delivering drugs to the lungs 220 1996
 
UNISIA JECS CORPORATION (2)
5647349 Medicine administering inhaling device 78 1996
5810004 Medicator for a capsule filled with a powdered drug 72 1996
 
BABAEV, EILAZ P. (1)
5076266 Device for ultrasonic atomizing of liquid medium 73 1990
 
TECHNOLOGY HOLDING COMPANY II (1)
* 6725858 Valved aerosol tee adapter assembly 16 2001
 
GENERAL ELECTRIC COMPANY (2)
6163588 Core plate and reactor internal pump differential pressure lines for a boiling water reactor 29 1998
2005/0284,469 Integrated control of ventilator and nebulizer operation 23 2005
 
QDOSE LIMITED (1)
5993805 Spray-dried microparticles and their use as therapeutic vehicles 179 1995
 
GLAXO AUSTRALIA PTY., LTD., (1)
D369212 Ampoule 52 1995
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (4)
2004/0035,413 Methods, devices and formulations for targeted endobronchial therapy 27 2003
2005/0211,245 Methods, devices and formulations for targeted endobronchial therapy 16 2004
2005/0235,987 Methods, devices and formulations for targeted endobronchial therapy 27 2005
2005/0211,253 Methods, devices and formulations for targeted endobronchial therapy 16 2005
 
YKK CORPORATION (1)
5910698 Method and apparatus for controlling piezoelectric vibration 34 1997
 
SEPRACOR INC. (1)
6161536 Dosage form for aerosol administration 60 1998
 
HOSPIRA, INC. (1)
5775506 Pharmaceutical ampul 28 1996
 
TRUDELL MEDICAL INTERNATIONAL (2)
5823179 Nebulizer apparatus and method 131 1996
2005/0039,746 Ventilator circuit and the method for the use thereof 24 2004
 
PARI GMBH SPEZIALISTEN FUER EFFEKTIVE INHALATION (1)
5549102 Nebulizer, especially for application in devices for inhalation therapy 79 1994
 
EASTMAN KODAK COMPANY (1)
4971665 Method of fabricating orifice plates with reusable mandrel 34 1989
 
MAQUET CRITICAL CARE AB (2)
4819629 Method and apparatus for delivering aerosol to the airways and/or lungs of a patient 323 1987
6032665 Dosing device for adding an additive fluid to breathing gas in an anaesthesia machine or ventilator 36 1997
 
ULRICH BUCHHOLTZ (1)
5435297 Medical device for inhaling metered aerosols 57 1994
 
MATSUSHITA ELECTRIC WORKS, LTD. (1)
4479609 Liquid sprayer 75 1982
 
MERCK PATENT GMBH (1)
4964521 Ampuls and apparatus thereon for opening same 33 1989
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (5)
4465234 Liquid atomizer including vibrator 93 1981
4533082 Piezoelectric oscillated nozzle 129 1982
4605167 Ultrasonic liquid ejecting apparatus 119 1983
4530464 Ultrasonic liquid ejecting unit and method for making same 75 1983
4632311 Atomizing apparatus employing a capacitive piezoelectric transducer 80 1983
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (4)
* 2006/0254,579 Ventilator circuit and method for the use thereof 14 2006
* 2008/0119,779 Method of Treating Lumens, Cavities, and Tissues of the Body with an Ultrasound Delivered Liquid. 1 2006
9573154 Dispensing aerosols 0 2012
9675769 Drug dispensing controller and monitoring system for a ventilator 0 2014
 
IDTX SYSTEMS, INC. (4)
8857429 Drug delivery and monitoring system for a ventilator 1 2008
* 2008/0308,101 DRUG DELIVERY AND MONITORING SYSTEM FOR A VENTILATOR 8 2008
8869793 Compact self-contained automated MDI adapters or units for ventilators 1 2011
9216267 Compact self-contained automated MDI adapters or units for ventilators 0 2014
 
MALLINCKRODT DEVELOPPEMENT FRANCE S.A.S. (2)
9084865 System and method for regulating a heating humidifier 0 2007
* 2007/0284,361 SYSTEM AND METHOD FOR REGULATING A HEATING HUMIDIFIER 116 2007
 
KAER BIOTHERAPEUTICS CORPORATION (1)
9573147 Aerosolizing nozzle and method of operating such aerosolizing nozzle 0 2016
 
NEKTAR THERAPEUTICS (1)
9108211 Vibration systems and methods 1 2006
 
BAYER HEALTHCARE AG (1)
* 2009/0288,658 Antibiotic Formulations, Unit Doses, Kits, and Methods 11 2008
 
BAYER INTELLECTUAL PROPERTY GMBH (2)
9351929 Antibiotic formulations, unit doses, kits, and methods 0 2012
9351930 Antibiotic formulations, unit doses, kits, and methods 0 2012
 
ROVI GUIDES, INC. (1)
9363553 Electronic program guide with digital storage 0 2015
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (2)
* 8245708 Methods, devices and formulations for targeted endobronchial therapy 6 2003
* 2004/0035,413 Methods, devices and formulations for targeted endobronchial therapy 27 2003
 
WINDTREE THERAPEUTICS, INC. (4)
9592361 Ventilation circuit adaptor and proximal aerosol delivery system 0 2009
* 2011/0011,395 VENTILATION CIRCUIT ADAPTOR AND PROXIMAL AEROSOL DELIVERY SYSTEM 3 2009
8701658 Ventilation circuit adaptor and proximal aerosol delivery system 0 2012
9352114 Ventilation circuit adaptor and proximal aerosol delivery system 0 2014
 
TRUDELL MEDICAL INTERNATIONAL (11)
7849853 Ventilator circuit and the method for the use thereof 5 2004
* 8028697 Ventilator circuit and method for the use thereof 3 2006
8151794 Aerosol delivery system 4 2008
* 2008/0264,412 AEROSOL DELIVERY SYSTEM 13 2008
8905026 Ventilator circuit and method for the use thereof 0 2011
8663069 Respiratory muscle endurance training device and method for the use thereof 1 2012
8875706 Aerosol delivery system 0 2012
8758202 Respiratory muscle endurance training device and method for the use thereof 2 2012
9242057 Modular aerosol delivery system 0 2013
9642980 Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof 0 2014
9468735 Ventilator circuit and method for the use thereof 0 2014
 
PARION SCIENCES, INC. (5)
8551534 Inhaled hypertonic saline delivered by a heated nasal cannula 12 2008
* 2009/0104,272 INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA 13 2008
8778383 Methods of treatment 1 2012
8945605 Aerosol delivery systems, compositions and methods 1 2013
9408988 Inhaled hypertonic saline delivered by a heated nasal cannula 0 2013
 
Bacoustics, LLC (1)
* 8050752 Method of treating lumens, cavities, and tissues of the body with an ultrasound delivered liquid 1 2006
* Cited By Examiner

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 10, 2018
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00