Method and composition for the treatment of lung surfactant deficiency or dysfunction

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7201167
APP PUB NO 20050229926A1
SERIAL NO

11080279

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of treating a disease involving surfactant deficiency or dysfunction in a patient's lungs is disclosed comprising the steps of providing a liquid lung surfactant composition; aerosolizing the lung surfactant composition with a vibrating aperture-type aerosol generator to form a surfactant aerosol; and introducing the surfactant aerosol into the gas flow within a circuit of a pressure-assisted breathing system coupled to the patient's respiratory system, whereby a therapeutically effective amount of said surfactant is delivered to the patient's lungs. Apparatus is also disclosed that increases the efficiency of delivery of aerosolized medicaments such as aerosolized lung surfactant.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
NOVARTIS AGBASEL2831

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fink, James San Mateo, CA 8 560
Ivri, Yehuda Newport Beach, CA 47 2023

Cited Art Landscape

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5664557 Releasably engageable coupling for an inhaler 66 1995
 
AT&T LABS, INC. (2)
5024733 Palladium alloy electroplating process 58 1990
5180482 Thermal annealing of palladium alloys 43 1991
 
WELLDYNAMICS, B.V. (1)
6223746 Metered dose inhaler pump 86 1998
 
Automatic Liquid Packaging, Inc. (1)
4298045 Dispensing container with plural removable closure means unitary therewith 57 1980
 
Respirogenics Corporation (1)
5666946 Apparatus for delivering drugs to the lungs 225 1996
 
UNISIA JECS CORPORATION (2)
5647349 Medicine administering inhaling device 80 1996
5810004 Medicator for a capsule filled with a powdered drug 72 1996
 
BABAEV, EILAZ P. (1)
5076266 Device for ultrasonic atomizing of liquid medium 73 1990
 
TECHNOLOGY HOLDING COMPANY II (1)
* 6725858 Valved aerosol tee adapter assembly 18 2001
 
GENERAL ELECTRIC COMPANY (2)
6163588 Core plate and reactor internal pump differential pressure lines for a boiling water reactor 29 1998
2005/0284,469 Integrated control of ventilator and nebulizer operation 24 2005
 
QDOSE LIMITED (1)
5993805 Spray-dried microparticles and their use as therapeutic vehicles 181 1995
 
GLAXO AUSTRALIA PTY., LTD., (1)
D369212 Ampoule 52 1995
 
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (4)
2004/0035,413 Methods, devices and formulations for targeted endobronchial therapy 27 2003
2005/0211,245 Methods, devices and formulations for targeted endobronchial therapy 16 2004
2005/0235,987 Methods, devices and formulations for targeted endobronchial therapy 29 2005
2005/0211,253 Methods, devices and formulations for targeted endobronchial therapy 16 2005
 
YKK CORPORATION (1)
5910698 Method and apparatus for controlling piezoelectric vibration 34 1997
 
SEPRACOR INC. (1)
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Hospira, Inc. (1)
5775506 Pharmaceutical ampul 28 1996
 
Trudell Medical International (2)
5823179 Nebulizer apparatus and method 134 1996
2005/0039,746 Ventilator circuit and the method for the use thereof 26 2004
 
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5549102 Nebulizer, especially for application in devices for inhalation therapy 83 1994
 
EASTMAN KODAK COMPANY (1)
4971665 Method of fabricating orifice plates with reusable mandrel 34 1989
 
MAQUET CRITICAL CARE AB (2)
4819629 Method and apparatus for delivering aerosol to the airways and/or lungs of a patient 327 1987
6032665 Dosing device for adding an additive fluid to breathing gas in an anaesthesia machine or ventilator 36 1997
 
ULRICH BUCHHOLTZ (1)
5435297 Medical device for inhaling metered aerosols 58 1994
 
MATSUSHITA ELECTRIC WORKS, LTD. (1)
4479609 Liquid sprayer 75 1982
 
MERCK PATENT GMBH (1)
4964521 Ampuls and apparatus thereon for opening same 33 1989
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (5)
4465234 Liquid atomizer including vibrator 93 1981
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4632311 Atomizing apparatus employing a capacitive piezoelectric transducer 80 1983
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
* 2006/0254,579 Ventilator circuit and method for the use thereof 15 2006
* 2008/0119,779 Method of Treating Lumens, Cavities, and Tissues of the Body with an Ultrasound Delivered Liquid. 1 2006
9573154 Dispensing aerosols 0 2012
 
IDTX SYSTEMS, INC. (5)
8857429 Drug delivery and monitoring system for a ventilator 1 2008
* 2008/0308,101 DRUG DELIVERY AND MONITORING SYSTEM FOR A VENTILATOR 11 2008
8869793 Compact self-contained automated MDI adapters or units for ventilators 2 2011
9675769 Drug dispensing controller and monitoring system for a ventilator 0 2014
9216267 Compact self-contained automated MDI adapters or units for ventilators 1 2014
 
MALLINCKRODT DEVELOPPEMENT FRANCE S.A.S. (2)
9084865 System and method for regulating a heating humidifier 0 2007
* 2007/0284,361 SYSTEM AND METHOD FOR REGULATING A HEATING HUMIDIFIER 116 2007
 
KAER BIOTHERAPEUTICS CORPORATION (1)
9573147 Aerosolizing nozzle and method of operating such aerosolizing nozzle 0 2016
 
NEKTAR THERAPEUTICS (1)
9108211 Vibration systems and methods 2 2006
 
BAYER HEALTHCARE AG (1)
* 2009/0288,658 Antibiotic Formulations, Unit Doses, Kits, and Methods 11 2008
 
BAYER INTELLECTUAL PROPERTY GMBH (2)
9351929 Antibiotic formulations, unit doses, kits, and methods 0 2012
9351930 Antibiotic formulations, unit doses, kits, and methods 0 2012
 
ROVI GUIDES, INC. (1)
9363553 Electronic program guide with digital storage 0 2015
 
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (2)
* 8245708 Methods, devices and formulations for targeted endobronchial therapy 6 2003
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9592361 Ventilation circuit adaptor and proximal aerosol delivery system 0 2009
* 2011/0011,395 VENTILATION CIRCUIT ADAPTOR AND PROXIMAL AEROSOL DELIVERY SYSTEM 4 2009
8701658 Ventilation circuit adaptor and proximal aerosol delivery system 0 2012
9352114 Ventilation circuit adaptor and proximal aerosol delivery system 0 2014
 
Trudell Medical International (11)
7849853 Ventilator circuit and the method for the use thereof 6 2004
* 8028697 Ventilator circuit and method for the use thereof 3 2006
8151794 Aerosol delivery system 5 2008
* 2008/0264,412 AEROSOL DELIVERY SYSTEM 13 2008
8905026 Ventilator circuit and method for the use thereof 0 2011
8663069 Respiratory muscle endurance training device and method for the use thereof 1 2012
8875706 Aerosol delivery system 0 2012
8758202 Respiratory muscle endurance training device and method for the use thereof 2 2012
9242057 Modular aerosol delivery system 0 2013
9642980 Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof 0 2014
9468735 Ventilator circuit and method for the use thereof 0 2014
 
PARION SCIENCES, INC. (5)
8551534 Inhaled hypertonic saline delivered by a heated nasal cannula 13 2008
* 2009/0104,272 INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA 14 2008
8778383 Methods of treatment 1 2012
8945605 Aerosol delivery systems, compositions and methods 3 2013
9408988 Inhaled hypertonic saline delivered by a heated nasal cannula 0 2013
 
Bacoustics, LLC (1)
* 8050752 Method of treating lumens, cavities, and tissues of the body with an ultrasound delivered liquid 1 2006
* Cited By Examiner

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