Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
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United States of America Patent
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Apr 10, 2007
Grant Date -
Dec 30, 2004
app pub date -
Jul 15, 2002
filing date -
Jul 30, 2001
priority date (Note) -
Expired
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of acyl CoA cholesterol acyltransferase-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding acyl CoA cholesterol acyltransferase-2. Methods of using these compounds for modulation of acyl CoA cholesterol acyltransferase-2 expression and for treatment of diseases associated with expression of acyl CoA cholesterol acyltransferase-2 are provided.
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