Hydrogel-based prosthetic device for replacing at least a part of the nucleus of a spinal disc

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United States of America Patent

PATENT NO 7204897
SERIAL NO

10830578

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is a prosthetic for replacement of at least a part of the nucleus of a intravertebral disc. The prosthetic device is composed of at least two essentially parallel soft layers of an elastically deformable hydrogel and at least one rigid layer, the rigid layer having less compressibility than the soft layers, being adjacent to the soft layers, parallel to them, and firmly attached to them. In some embodiments, the soft layers have the same thickness and composition. Typically, the prosthesis has more than one rigid layer and these rigid layers have the same thickness and composition. The number of soft layers is usually one more than the number of rigid layers, with, e.g., at least three soft layers. The invention also includes a method of prosthesis production, which involves prefabricating soft and rigid layers; stacking at least two prefabricated soft and at least one prefabricated rigid layer in a parallel fashion into their final form, and, permitting the layers to firmly connect to one another by mutual interaction. In this method, at least one type of the layers is prefabricated in the dehydrated state, which is done by dehydrating stretched foil in an apparatus preventing its contraction and thereby decreasing its area. There is at least partial dehydration of the prosthesis under pressure applied in a direction tangent to the planes of the layers. In preferred embodiments, while in the state of almost full dehydration, is sterilized using ionizing radiation or a gaseous chemical agent, after which it is partially rehydrated within the sterile wrapper using water vapor.

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Patent Owner(s)

  • REPLICATION MEDICAL, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drunecky, Tomas Kladno, CZ 5 245
Kozlova, Zdena Beroun, CZ 4 237
Stehlicek, Petr Kladno, CZ 7 237
Stoy, Vladimir A Princeton, NJ 32 2424

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