US Patent No: 7,208,011

Number of patents in Portfolio can not be more than 2000

Implantable medical device with drug filled holes

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ALSO PUBLISHED AS: 20030068355
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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to implantable medical devices for delivery of therapeutic agents, such as drugs, to a patient. More particularly, the invention relates to a device having therapeutic agents protected by a protective layer that prevents or retards processes that deactivate or degrade the active agents.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
CONOR MEDSYSTEMS, INC.NEW BRUNSWICK, NJ11

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Parker, Theodore L Danville, CA 115 1583
Shanley, John F Redwood City, CA 154 2307

Cited Art Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (39)
5,304,121 Drug delivery system making use of a hydrogel polymer coating 484 1991
5,234,456 Hydrophilic stent 486 1992
5,439,446 Stent and therapeutic delivery system 248 1994
6,515,009 Therapeutic inhibitor of vascular smooth muscle cells 63 1995
5,811,447 Therapeutic inhibitor of vascular smooth muscle cells 186 1995
5,578,075 Minimally invasive bioactivated endoprosthesis for vessel repair 247 1995
5,628,787 Clad composite stent 179 1995
6,171,609 Therapeutic inhibitor of vascular smooth muscle cells 172 1995
5,843,117 Implantable vascular and endoluminal stents and process of fabricating the same 171 1996
5,837,313 Drug release stent coating process 606 1996
6,120,536 Medical devices with long term non-thrombogenic coatings 522 1996
5,824,045 Vascular and endoluminal stents 197 1996
5,868,781 Locking stent 183 1996
5,733,925 Therapeutic inhibitor of vascular smooth muscle cells 365 1996
5,981,568 Therapeutic inhibitor of vascular smooth muscle cells 256 1997
6,306,421 Therapeutic inhibitor of vascular smooth muscle cells 80 1997
5,922,021 Intravascular stent 229 1997
5,980,972 Method of applying drug-release coatings 445 1997
5,972,027 Porous stent drug delivery system 349 1997
6,358,556 Drug release stent coating 360 1998
5,984,957 Radially expanded prostheses with axial diameter control 166 1998
6,280,411 Localized delivery of drug agents 143 1998
6,022,371 Locking stent 119 1998
6,099,561 Vascular and endoluminal stents with improved coatings 282 1998
6,120,847 Surface treatment method for stent coating 204 1999
6,249,952 Method for manufacturing an expandable stent 95 1999
6,231,600 Stents with hybrid coating for medical devices 337 1999
6,358,989 Therapeutic inhibitor of vascular smooth muscle cells 47 1999
6,268,390 Therapeutic inhibitor of vascular smooth muscle cells 72 1999
6,491,666 Microfabricated devices for the delivery of molecules into a carrier fluid 193 2000
6,491,938 Therapeutic inhibitor of vascular smooth muscle cells 84 2001
6,599,928 Therapeutic inhibitor of vascular smooth muscle cells 48 2001
6,569,441 Therapeutic inhibitor of vascular smooth muscle cells 68 2001
6,663,881 Therapeutic inhibitor of vascular smooth muscle cells 58 2001
2002/0071,902 Drug release stent coating 45 2002
6,645,547 Stent coating device 130 2002
6,537,256 Microfabricated devices for the delivery of molecules into a carrier fluid 108 2002
6,656,162 Implantable drug delivery stents 189 2002
6,720,350 Therapeutic inhibitor of vascular smooth muscle cells 41 2002
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (35)
5,242,399 Method and system for stent delivery 328 1992
5,342,621 Antithrombogenic surface 248 1992
5,344,426 Method and system for stent delivery 381 1993
5,441,515 Ratcheting stent 476 1993
5,556,413 Coiled stent with locking ends 280 1994
5,443,500 Intravascular stent 440 1994
5,707,385 Drug loaded elastic membrane and method for delivery 257 1994
5,605,696 Drug loaded polymeric material and method of manufacture 586 1995
5,593,434 Stent capable of attachment within a body lumen 265 1995
5,618,299 Ratcheting stent 259 1995
5,725,549 Coiled stent with locking ends 244 1996
5,827,322 Shape memory locking mechanism for intravascular stents 83 1996
5,733,330 Balloon-expandable, crush-resistant locking stent 139 1997
5,759,192 Method and apparatus for direct laser cutting of metal stents 201 1997
5,843,172 Porous medicated stent 357 1997
6,240,616 Method of manufacturing a medicated porous metal prosthesis 410 1997
5,766,239 Balloon-expandable, crush resistant locking stent and method of loading the same 127 1997
5,976,182 Balloon-expandable, crush-resistant locking stent and method of loading the same 133 1998
6,273,910 Stent with varying strut geometry 136 1999
6,379,381 Porous prosthesis and a method of depositing substances into the pores 369 1999
6,713,119 Biocompatible coating for a prosthesis and a method of forming the same 179 1999
6,395,326 Apparatus and method for depositing a coating onto a surface of a prosthesis 432 2000
6,585,765 Implantable device having substances impregnated therein and a method of impregnating the same 240 2000
6,503,954 Biocompatible carrier containing actinomycin D and a method of forming the same 212 2000
6,254,632 Implantable medical device having protruding surface structures for drug delivery and cover attachment 433 2000
6,716,444 Barriers for polymer-coated implantable medical devices and methods for making the same 240 2000
6,506,437 Methods of coating an implantable device having depots formed in a surface thereof 325 2000
6,558,733 Method for etching a micropatterned microdepot prosthesis 279 2000
6,759,054 Ethylene vinyl alcohol composition and coating 128 2000
2002/0123,801 Diffusion barrier layer for implantable devices 163 2000
2002/0142,039 Controlled morphologies in polymer drug for release of drugs from polymer films 122 2001
6,712,845 Coating for a stent and a method of forming the same 244 2001
2002/0155,212 Coating for a stent and a method of forming the same 216 2001
6,660,034 Stent for increasing blood flow to ischemic tissues and a method of using the same 232 2001
6,673,385 Methods for polymeric coatings stents 185 2001
 
CORDIS CORPORATION (13)
4,739,762 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 1047 1986
5,102,417 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 775 1988
4,994,071 Bifurcating stent apparatus and method 905 1989
5,049,132 Balloon catheter for delivering therapeutic agents 375 1990
5,171,262 Non-woven endoprosthesis 337 1990
5,195,984 Expandable intraluminal graft 607 1991
5,607,442 Stent with improved radiopacity and appearance characteristics 305 1995
5,882,335 Retrievable drug delivery stent 139 1996
6,140,127 Method of coating an intravascular stent with an endothelial cell adhesive five amino acid peptide 89 1998
6,017,363 Bifurcated axially flexible stent 181 1998
6,273,913 Modified stent useful for delivery of drugs along stent strut 536 1998
6,723,373 Device and process for coating stents 62 2000
6,585,764 Stent with therapeutically active dosage of rapamycin coated thereon 153 2001
 
MEDTRONIC, INC. (13)
4,969,458 Intracoronary stent and method of simultaneous angioplasty and stent implant 477 1987
5,957,971 Intraluminal stent 63 1993
5,443,496 Intravascular radially expandable stent 392 1993
5,545,208 Intralumenal drug eluting prosthesis 288 1993
5,800,507 Intraluminal stent 114 1995
5,837,008 Intravascular stent and method 332 1995
5,624,411 Intravascular stent and method 502 1995
5,679,400 Intravascular stent and method 428 1995
5,776,184 Intravasoular stent and method 358 1996
5,928,916 Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces 70 1998
6,206,914 Implantable system with drug-eluting cells for on-demand local drug delivery 195 1998
6,730,116 Medical device for intraluminal endovascular stenting 96 1999
6,399,144 Medical device for delivering a therapeutic substance and method therefor 50 2001
 
MED INSTITUTE, INC. (8)
5,380,299 Thrombolytic treated intravascular medical device 384 1993
5,609,629 Coated implantable medical device 629 1995
6,096,070 Coated implantable medical device 753 1996
5,824,049 Coated implantable medical device 725 1996
5,873,904 Silver implantable medical device 720 1997
6,299,604 Coated implantable medical device 578 1999
6,730,064 Coated implantable medical device 212 2001
2003/0036,794 Coated implantable medical device 255 2002
 
PONIARD PHARMACEUTICALS, INC. (7)
5,472,985 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells 43 1994
5,545,569 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells 59 1995
5,595,722 Method for identifying an agent which increases TGF-beta levels 82 1995
5,770,609 Prevention and treatment of cardiovascular pathologies 90 1995
5,599,844 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells 49 1995
5,773,479 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells 33 1995
5,945,456 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells 36 1997
 
ANGIOTECH PHARMACEUTICALS, INC. (5)
5,716,981 Anti-angiogenic compositions and methods of use 651 1995
5,886,026 Anti-angiogenic compositions and methods of use 204 1995
5,994,341 Anti-angiogenic Compositions and methods for the treatment of arthritis 64 1995
6,506,411 Anti-angiogenic compositions and methods of use 72 1999
6,544,544 Anti-angiogenic compositions and methods of use 130 2001
 
INNOVATIONAL HOLDINGS LLC (5)
6,241,762 Expandable medical device with ductile hinges 221 1998
6,290,673 Expandable medical device delivery system and method 142 1999
6,293,967 Expandable medical device with ductile hinges 106 1999
6,562,065 Expandable medical device with beneficial agent delivery mechanism 96 2000
6,764,507 Expandable medical device with improved spatial distribution 70 2001
 
MEDTRONIC AVE, INC. (5)
5,817,152 Connected stent apparatus 97 1995
6,156,062 Helically wrapped interlocking stent 138 1997
6,206,915 Drug storing and metering stent 146 1998
2002/0127,263 Peroxisome proliferator-acitvated receptor gamma ligand eluting medical device 24 2002
2003/0204,239 Endovascular stent with a preservative coating 43 2002
 
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (5)
5,157,049 Method of treating cancers sensitive to treatment with water soluble derivatives of taxol 85 1991
5,616,608 Method of treating atherosclerosis or restenosis using microtubule stabilizing agent 160 1996
6,429,232 Method of treating atherosclerosis or restenosis using microtubule stabilizing agent 43 1997
6,403,635 Method of treating atherosclerosis or restenosis using microtubule stabilizing agent 55 2000
6,500,859 Method for treating atherosclerosis or restenosis using microtubule stabilizing agent 20 2002
 
WYETH (5)
2001/0029,351 Drug combinations and delivery devices for the prevention and treatment of vascular disease 245 2001
2002/0005,206 Antiproliferative drug and delivery device 203 2001
2002/0007,213 Drug/drug delivery systems for the prevention and treatment of vascular disease 186 2001
2002/0007,214 Drug/drug delivery systems for the prevention and treatment of vascular disease 181 2001
2002/0007,215 Drug/drug delivery systems for the prevention and treatment of vascular disease 189 2001
 
COOK MEDICAL TECHNOLOGIES LLC (4)
5,843,175 Enhanced flexibility surgical stent 182 1997
6,042,606 Radially expandable non-axially contracting surgical stent 182 1997
2003/0028,243 Coated implantable medical device 240 2002
2003/0028,244 Coated implantable medical device 193 2002
 
FEMORALIS, LLC (4)
6,245,101 Intravascular hinge stent 92 1999
6,312,460 Intravascular hinge stent 44 2001
6,451,051 Intravascular folded tubular endoprosthesis 45 2001
6,475,237 Intravascular hinge stent 57 2001
 
MEDINOL LTD. (4)
5,449,373 Articulated stent 659 1994
5,807,404 Stent with variable features to optimize support and method of making such stent 261 1996
5,843,120 Flexible-expandable stent 222 1997
2002/0022,876 Longitudinally flexible stent 46 2001
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (3)
5,843,741 Method for altering the differentiation of anchorage dependent cells on an electrically conducting polymer 52 1994
5,797,898 Microchip drug delivery devices 309 1996
6,123,861 Fabrication of microchip drug delivery devices 174 1998
 
SCIMED LIFE SYSTEMS, INC. (3)
5,464,450 Biodegradable drug delivery vascular stent 269 1994
5,551,954 Biodegradable drug delivery vascular stent 275 1994
5,769,883 Biodegradable drug delivery vascular stent 288 1995
 
VASCULAR CONCEPTS HOLDINGS LIMITED (3)
5,725,548 Self-locking stent and method for its production 42 1996
5,713,949 Microporous covered stents and method of coating 240 1996
6,056,722 Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and methods of use 158 1997
 
BIOCOMPATIBLES UK LIMITED (2)
6,497,916 Coating 34 2000
6,746,686 Coated implants 20 2001
 
CALMEDICA, LLC (2)
5,197,978 Removable heat-recoverable tissue supporting device 483 1991
5,545,210 Method of implanting a permanent shape memory alloy stent 294 1994
 
CID S.P.A. (2)
6,309,414 Angioplasty stents 138 1997
6,638,302 Stent for angioplasty and associated production process 89 1997
 
COOK INCORPORATED (2)
4,580,568 Percutaneous endovascular stent and method for insertion thereof 1171 1984
4,800,882 Endovascular stent and delivery system 1213 1987
 
Eli Lilly and Company (2)
5,314,688 Local delivery of dipyridamole for the treatment of proliferative diseases 70 1993
5,457,113 Methods for inhibiting vascular smooth muscle cell proliferation and restinosis 92 1993
 
EMORY UNIVERSITY (2)
5,383,928 Stent sheath for local drug delivery 378 1993
5,523,092 Device for local drug delivery and methods for using the same 141 1994
 
ENDOSONICS CORPORATION (2)
5,643,314 Self-expanding stent 68 1995
5,876,419 Stent and method for making a stent 117 1997
 
ETHICON, INC. (2)
6,153,252 Process for coating stents 619 1999
6,423,092 Biodegradable stent 147 2001
 
Medical Innovative Technologies R&D Limited Partnership (2)
5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia 420 1989
5,176,617 Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct 225 1991
 
SUMMERS, DAVID (2)
4,955,878 Kit for preventing or treating arterial dysfunction resulting from angioplasty procedures 50 1988
5,980,551 Composition and method for making a biodegradable drug delivery stent 132 1997
 
ABBOTT LABORATORIES (1)
5,922,020 Tubular prosthesis having improved expansion and imaging characteristics 238 1996
 
ABRAXIS BIOSCIENCE, LLC (1)
5,439,686 Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor 169 1993
 
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (1)
5,171,217 Method for delivery of smooth muscle cell inhibitors 287 1991
 
ALZA CORPORATION (1)
6,071,305 Directional drug delivery stent and method of use 374 1997
 
Angiobrade Partners (1)
4,650,466 Angioplasty device 697 1985
 
AVANTEC VASCULAR CORPORATION (1)
2002/0082,679 Delivery or therapeutic capable agents 253 2001
 
BIOSENSORS INTERNATIONAL USA (1)
2003/0088,307 Potent coatings for stents 130 2002
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (1)
5,935,506 Method for the manufacture of intraluminal stents of bioresorbable polymeric material 69 1996
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
2003/0050,687 Biocompatible stents and method of deployment 66 2001
 
BOSTON SCIENTIFIC CORPORATION (1)
5,968,092 Method for making a biodegradable stent 144 1998
 
BOSTON SCIENTIFIC LIMITED (1)
6,306,166 Loading and release of water-insoluble drugs 148 1998
 
CARBOMEDICS INC. (1)
4,300,244 Cardiovascular grafts 218 1979
 
CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (1)
5,460,817 Particulate composition comprising a core of matrix polymer with active ingredient distributed therein 62 1993
 
CORVITA CORPORATION (1)
5,019,090 Radially expandable endoprosthesis and the like 707 1988
 
COVIDIEN LP (1)
5,964,798 Stent having high radial strength 119 1997
 
DUKE UNIVERSITY (1)
5,059,211 Absorbable vascular stent 487 1987
 
ECC INTERNATIONAL INC. (1)
6,719,881 Acid colloid in a microparticle system used in papermaking 8 2001
 
EXPANDABLE GRAFTS PARTNERSHIP, 8000 I.H. 10 WEST, STE. 1265, SAN ANTONIO, TX A GENERAL PARTNERSHIP OF TX. (1)
4,733,665 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 2116 1985
 
EXPANDABLE GRAFTS PARTNERSHIP, A TX. GENERAL PARTNERSHIP (1)
4,776,337 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 1122 1986
 
GALDERMA RESEARCH & DEVELOPMENT (1)
5,292,512 Cosmetic or pharmaceutical composition containing microspheres of polymers or of fatty substances filled with at least one active product 57 1989
 
GENESIS MICROCHIP INC. (1)
6,551,838 Microfabricated devices for the storage and selective exposure of chemicals and devices 130 2001
 
GENZYME CORPORATION (1)
5,213,580 Biodegradable polymeric endoluminal sealing process 276 1992
 
GORDON, DAVID, SKOKIE, ILLINOIS (1)
4,531,936 Device and method for the selective delivery of drugs to the myocardium 183 1983
 
Harbor Medical Devices, Inc. (1)
5,447,724 Medical device polymer 406 1993
 
ICON INTERVENTIONAL SYSTEMS, INC. (1)
6,206,916 Coated intraluminal graft 135 1999
 
ISOSTENT, INC. (1)
5,697,971 Multi-cell stent with cells having differing characteristics 455 1996
 
LATHAM, DANIEL W. (1)
5,464,650 Intravascular stent and method 740 1993
 
LEMAITRE VASCULAR, INC. (1)
2002/0082,682 Biologically active agent delivery apparatus and method 66 2001
 
LIFESHIELD SCIENCES LLC (1)
5,053,048 Thromboresistant coating 214 1990
 
MAYA, LLC (1)
6,083,258 Locking stent 112 1998
 
MEADOX MEDICALS, INC. (1)
5,383,892 Stent for transluminal implantation 572 1992
 
MEDICAL ENGINEERING AND DEVELOPMENT INSTITUTE, INC. (1)
4,989,601 Method, apparatus, and substance for treating tissue having neoplastic cells 94 1988
 
Mediplex Corporation, Korea (1)
6,702,850 Multi-coated drug-eluting stent for antithrombosis and antirestenosis 53 2002
 
MEDSTENT INC. (1)
5,776,181 Expandable stent 107 1996
 
MEDTRONIC VASCULAR, INC. (1)
5,674,278 Endovascular support device 81 1996
 
NEC ELECTRONICS CORPORATION (1)
5,855,600 Flexible implantable stent with composite design 291 1997
 
NEXSTAR PHARMACEUTICALS, INC. (1)
5,441,745 Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body 31 1984
 
NFOCUS NEUROMEDICAL, INC. (1)
5,853,419 Stent 174 1997
 
NITROMED, INC. (1)
6,087,479 Localized use of nitric oxide-adducts to prevent internal tissue damage 81 1995
 
NoeRx Corporation (1)
6,074,659 Therapeutic inhibitor of vascular smooth muscle cells 207 1998
 
ORTHO-MCNEIL PHARMACEUTICAL, INC. (1)
6,627,246 Process for coating stents and other medical devices using super-critical carbon dioxide 45 2001
 
PDT Systems, Inc. (1)
5,419,760 Medicament dispensing stent for prevention of restenosis of a blood vessel 230 1994
 
PHARMACIA & UPJOHN S.P.A. (1)
5,473,055 Polymer-bound paclitaxel derivatives 66 1994
 
PRECISION VASCULAR SYSTEMS, INC. (1)
6,063,101 Stent apparatus and method 187 1998
 
Quanam Medical Corporation (1)
6,019,789 Expandable unit cell and intraluminal stent 192 1998
 
Radiance Medical Systems, Inc. (1)
6,120,535 Microporous tubular prosthesis 98 1997
 
RESEARCH CORPORATION TECHNOLOGIES, INC. (1)
5,407,683 Pharmaceutical solutions and emulsions containing taxol 59 1992
 
RESEARCH DEVELOPMENT CORPORATION OF JAPAN (1)
5,449,513 Physical trapping type polymeric micelle drug preparation 84 1993
 
RHONE-POULENC RORER S.A. (1)
5,403,858 New compositions containing taxane derivatives 58 1993
 
Schneider (Europe) A.G. (1)
5,534,287 Methods for applying an elastic coating layer on stents 80 1994
 
SIVAN, SARIT (1)
6,569,688 Intravascular apparatus method 28 2000
 
SORIN BIOMEDICA CARDIO S.P.A. (1)
6,572,642 Method for treating a prosthesis having an apertured structure and associated devices 57 2002
 
SOUTHERN RESEARCH INSTITUTE (1)
4,542,025 Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents 135 1984
 
STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (1)
6,159,488 Intracoronary stents containing quinazolinone derivatives 46 1999
 
STRYKER TECHNOLOGIES CORPORATION (1)
4,834,755 Triaxially-braided fabric prosthesis 225 1985
 
SURMODICS, INC. (1)
6,121,027 Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups 381 1997
 
TAHERI ENTERPRISES, LLC (1)
5,617,878 Stent and method for treatment of aortic occlusive disease 300 1996
 
TAHERI LADUCA LLC (1)
6,030,414 Variable stent and method for treatment of arterial disease 178 1997
 
TERUMO KABUSHIKI KAISHA (1)
6,174,326 Radiopaque, antithrombogenic stent and method for its production 69 1997
 
The Johns Hopkins University (1)
5,443,497 Percutaneous prosthetic by-pass graft and method of use 449 1993
 
The Penn State Research Foundation (1)
6,682,545 System and device for preventing restenosis in body vessels 38 2000
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
5,992,769 Microchannel system for fluid delivery 89 1995
 
The Research Foundation of State University of New York (1)
5,415,869 Taxol formulation 83 1993
 
TRUSTEES OF BOSTON UNIVERSITY (1)
5,665,591 Regulation of smooth muscle cell proliferation 34 1994
 
UBE INDUSTRIES, LTD. (1)
4,957,508 Medical tubes 149 1987
 
UNITED STENTING INCORPORATED (1)
2001/0044,652 Stents with multi-layered struts 173 2001
 
UNIVERSITY OF KANSAS, OFFICE OF RESEARCH GRADUATE STUDIES & PUBLIC SERVICE, (1)
4,960,790 Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof 261 1989
 
VANDERBILT UNIVERSITY (1)
5,462,866 Semipermeable microspheres encapsulating biological material 55 1993
 
VENTION MEDICAL ADVANCED COMPONENTS, INC. (1)
5,286,254 Drug delivery apparatus and method 356 1992
 
WAYNE STATE UNIVERSITY (1)
5,092,841 Method for treating an arterial wall injured during angioplasty 398 1990
 
ZYNAXIS TECHNOLOGIES, INC. (1)
5,667,764 Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles 78 1992
 
Other [Check patent profile for assignment information] (15)
4,824,436 Method for the prevention of restenosis 241 1987
4,990,155 Surgical stent method and apparatus 334 1989
5,078,726 Graft stent and method of repairing blood vessels 446 1990
5,342,348 Method and device for treating and enlarging body lumens 456 1992
5,575,771 Balloon catheter with external guidewire 165 1995
5,741,293 Locking stent 67 1995
6,007,517 Rapid exchange/perfusion angioplasty catheter 140 1996
6,193,746 Endoprosthesis that can be percutaneously implanted in the patient's body 72 1996
6,273,908 Stents 215 1997
6,239,118 Method for preventing restenosis using a substituted adenine derivative 23 1999
2002/0038,145 Intravascular stent with increasing coating retaining capacity 64 2001
2003/0077,312 Coated intraluminal stents and reduction of restenosis using same 32 2001
6,613,084 Stent having cover with drug delivery capability 67 2001
2003/0181,973 Reduced restenosis drug containing stents 61 2002
2004/0073,296 Inhibition of restenosis using a DNA-coated stent 17 2003

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (45)
8,137,397 Medical devices 0 2004
8,089,029 Bioabsorbable metal medical device and method of manufacture 1 2006
8,187,620 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 1 2006
8,048,150 Endoprosthesis having a fiber meshwork disposed thereon 1 2006
8,067,054 Stents with ceramic drug reservoir layer and methods of making and using the same 2 2007
7,976,915 Endoprosthesis with select ceramic morphology 1 2007
8,002,823 Endoprosthesis coating 1 2007
7,942,926 Endoprosthesis coating 1 2007
7,931,683 Articles having ceramic coated surfaces 12 2007
8,052,743 Endoprosthesis with three-dimensional disintegration control 0 2007
7,842,082 Bifurcated stent 1 2007
7,951,191 Bifurcated stent with entire circumferential petal 0 2007
8,353,949 Medical devices with drug-eluting coating 1 2007
7,959,669 Bifurcated stent with open ended side branch support 0 2007
8,052,744 Medical devices and methods of making the same 1 2007
8,052,745 Endoprosthesis 0 2007
8,002,821 Bioerodible metallic ENDOPROSTHESES 3 2007
8,128,689 Bioerodible endoprosthesis with biostable inorganic layers 1 2007
8,057,534 Bioerodible endoprostheses and methods of making the same 5 2007
7,981,150 Endoprosthesis with coatings 4 2007
8,216,632 Endoprosthesis coating 0 2007
8,029,554 Stent with embedded material 2 2007
7,938,855 Deformable underlayer for stent 2 2007
7,833,266 Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment 0 2007
8,277,501 Bi-stable bifurcated stent petal geometry 0 2007
8,080,055 Bioerodible endoprostheses and methods of making the same 0 2007
8,431,149 Coated medical devices for abluminal drug delivery 0 2008
8,070,797 Medical device with a porous surface for delivery of a therapeutic agent 2 2008
7,815,675 Stent with protruding branch portion for bifurcated vessels 1 2008
7,998,192 Endoprostheses 1 2008
8,236,046 Bioerodible endoprosthesis 0 2008
8,221,822 Medical device coating by laser cladding 0 2008
7,985,252 Bioerodible endoprosthesis 1 2008
8,382,824 Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides 0 2008
8,071,156 Endoprostheses 1 2009
8,287,937 Endoprosthese 1 2009
8,016,878 Bifurcation stent pattern 0 2009
8,449,603 Endoprosthesis coating 1 2009
7,951,192 Stent with protruding branch portion for bifurcated vessels 2 2009
8,231,980 Medical implants including iridium oxide 0 2009
8,267,992 Self-buffering medical implants 0 2010
8,066,763 Drug-releasing stent with ceramic-containing layer 0 2010
8,574,615 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 0 2010
8,668,732 Surface treated bioerodible metal endoprostheses 0 2011
8,425,590 Stent with protruding branch portion for bifurcated vessels 0 2011
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (6)
7,824,440 Stent with drug coating 3 2006
7,824,441 Stent with drug coating 3 2006
7,820,229 Method of coating a stent 3 2006
7,666,223 Stent with drug coating 4 2006
8,119,184 Method of making a variable surface area stent 1 2010
8,367,149 Method of coating a stent having variable drug release rate 1 2010
 
GREATBATCH LTD. (4)
8,057,543 Stent coating for eluting medication 1 2006
8,048,151 Stent coating for eluting medication 0 2009
8,066,764 Stent coating for eluting medication 0 2009
8,367,151 Stent coating for eluting medication 1 2010
 
AFFINERGY, LLC. (3)
7,608,581 Biofunctional, antimicrobial coatings for medical devices 1 2006
7,807,624 Methods and compositions for promoting attachment of cells of endothelial cell lineage to medical devices 0 2007
8,067,021 Methods and compositions for delivery of growth factor to fibrous connective tissue 0 2008
 
CORDIS CORPORATION (2)
7,972,373 Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts 0 2007
7,981,149 Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts 0 2010
 
INNOVATIONAL HOLDINGS LLC (2)
7,850,727 Expandable medical device for delivery of beneficial agent 3 2005
7,842,083 Expandable medical device with improved spatial distribution 0 2006
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (1)
8,628,568 Stent with drug coating with variable release rate 0 2010
 
PLS TECHNOLOGIES, LLC (1)
8,628,790 Coating system and method for drug elution management 0 2010
 
REMON MEDICAL TECHNOLOGIES LTD. (1)
8,303,643 Method and device for electrochemical formation of therapeutic species in vivo 0 2010
 
SYNTHES GMBH (1)
8,637,455 Compositions and methods for delivery of glycopeptide antibiotics to medical device surfaces 0 2008
 
SYNTHES USA, LLC (1)
7,977,313 Methods and compositions for promoting localization of pharmaceutically active agents to bone 0 2008

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Oct 24, 2014
11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 24, 2018
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00