Bioprocesses enhanced by magnetic nanoparticles
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United States of America Patent
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Apr 24, 2007
Grant Date -
Feb 23, 2006
app pub date -
Dec 20, 2004
filing date -
Dec 18, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
One aspect of the present invention relates to magnetic nanoparticles colloidally stabilized in aqueous milieu by association with an organic phase. The organic phase may be either a fluorinated polymer or an organic hydrocarbon bilayer, wherein the two layers are chemically bonded to each other. The stabilized particles are further non-toxic and provide useful enhancements in bioprocesses. Another aspect of the present invention relates to compositions comprising an oxygen-dissolving fluid vehicle and surface modified, nanometer-sized magnetic particles. The inventive compositions have utility in a wide range of applications, but are particularly suitable for use as recyclable oxygen carriers, separation and purification vehicles, and bioprocessing media, including fermentation processes.
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