Modulation of HIF1.alpha. and HIF2.alpha. expression

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United States of America Patent

PATENT NO 7217572
SERIAL NO

10719370

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Abstract

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Compounds, compositions and methods are provided for modulating the expression of HIF1.alpha. and/or HIF2.alpha.. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1.alpha. and HIF2.alpha.. Methods of using these compounds for modulation of HIF1.alpha. and/or HIF2.alpha. expression and for diagnosis and treatment of disease associated with expression of HIF1.alpha. and/or HIF2.alpha. are provided.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC1896 RUTHERFORD ROAD CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dobie, Kenneth W Del Mar, CA 319 3223
Freier, Susan M San Diego, CA 526 6555
Marcusson, Eric G San Diego, CA 63 1332
Ward, Donna T Murrieta, CA 62 1041

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