Methods and compositions for derepression of IAP-inhibited caspase

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United States of America Patent

PATENT NO 7217688
APP PUB NO 20060211627A1
SERIAL NO

11186629

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Abstract

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The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds.

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Patent Owner(s)

Patent OwnerAddress
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES3550 GENERAL ATOMICS COURT SAN DIEGO CA 92121-1122

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Houghten, Richard A Solana Beach, CA 84 1963
Nefzi, Adel San Diego, CA 27 222
Ostresh, John M Encinitas, CA 27 500
Pinilla, Clemencia Cardiff, CA 32 400
Reed, John C Rancho Santa Fe, CA 151 1433
Welsh, Kate San Diego, CA 8 111

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