Stabilizing a nucleic acid for nucleic acid sequencing
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United States of America Patent
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May 22, 2007
Grant Date -
Jul 6, 2006
app pub date -
Dec 30, 2004
filing date -
Dec 30, 2004
priority date (Note) -
Expired
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Abstract
The invention provides methods for sequencing a nucleic acid comprising stabilizing a primer/target nucleic acid duplex on a substrate. Methods of the invention generally contemplate the use of a dual-anchored primer/target nucleic acid duplex, or a stabilizing molecule in a single molecule sequencing reaction.
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