Expressing gp140 fragment of primary HIV-1 isolate

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United States of America Patent

PATENT NO 7220826
SERIAL NO

09914205

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Abstract

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A vector for eliciting an immune response to a host comprising a gene encoding the gp140 protein of the primary isolate of HIV-1, BX08, under the control of a promotor for expression of the protein in the host, specifically plasmids pCMV.gp140.BX08, pMP83, pMP84 and pMP88. Murine and human MHC class 1-restricted binding motifs contained in BX08 are identified.

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Patent Owner(s)

  • CONNAUGHT LABORATORIES LIMITED;SANOFI PASTEUR LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cao, Shi-Xian Stouffville, CA 22 188
Parrington, Mark Bradford, CA 23 118
Persson, Roy Toronto, CA 22 186
Rovinski, Benjamin Thornhill, CA 35 287
Sia, Charles D Y Thornhill, CA 12 124

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