Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
May 22, 2007
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jun 23, 1982
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention provides a nucleotide having the formula, ##STR00001## wherein PM is a phosphate moiety, SM is a ribose or a deoxyribose sugar moiety, and BASE is a pyrimidine, purine or 7-deazapurine moiety. PM is attached to SM at a position independently selected from the 2', 3', and 5' positions of SM when the nucleotide is a ribonucleotide, and at a position independently selected from the 3' and 5' positions when the nucleotide is a deoxyribonucleotide. BASE is attached to the 1' position of SM from the N.sup.1 position when BASE is a pyrimidine, or the N.sup.9 position when BASE is a purine or 7-deazapurine. Sig is a detectable moiety covalently attached to SM directly or through a linkage group. Also provided are an oligo- or polynucleotide comprising at least one such sugar moiety labeled nucleotide, and other compositions including those wherein a polypeptide is terminal ligated or attached to the oligo- or polynucleotide. The sugar moiety labeled nucleotide, and the oligo- or polynucleotides and other compositions comprising such nucleotides, are useful as diagnostic tools for detecting analytes and as therapeutic agents.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully