US Patent No: 7,223,399

Number of patents in Portfolio can not be more than 2000

Methods for treating restenosis with a botulinum neurotoxin

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ALSO PUBLISHED AS: 20060127417
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

The present invention provides for methods of treating cardiovascular diseases in a mammal. The methods include a step of administering an effective amount of a botulinum toxin directly to a blood vessel of a mammal thereby treating a cardiovascular disease.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ALLERGAN, INC.IRVINE, CA1477

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brooks, Gregory F Irvine, CA 29 116
Donovan, Stephen Capistrano Beach, CA 118 1462

Cited Art

Patent Info (Count) # Cites Year
 
ALLERGAN, INC. (10)
5,437,291 Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction 184 1993
6,977,080 Intrapericardial botulinum toxin treatment for bradycardia 2 1999
6,464,986 Method for treating pain by peripheral administration of a neurotoxin 68 2000
6,306,423 Neurotoxin implant 140 2000
6,312,708 Botulinum toxin implant 137 2000
6,383,509 Biodegradable neurotoxin implant 105 2001
6,767,544 Methods for treating cardiovascular diseases with botulinum toxin 22 2002
2003/0185,860 Methods for treating cardiovasular diseases with botulinum toxin 2 2002
7,048,927 Botulinum neurotoxin eluting stent 1 2003
2004/0223,975 Methods for treating cardiovascular diseases with botulinum toxin 1 2004
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (4)
5,865,794 Drug delivery catheter 18 1997
6,241,758 Self-expanding stent delivery system and method of use 36 1999
6,264,671 Stent delivery catheter and method of use 38 1999
6,306,162 Stent delivery system utilizing novel balloon for obtaining variable post-deployment stent characteristics 17 1999
 
BOSTON SCIENTIFIC SCIMED, INC. (2)
5,989,280 Stent delivery apparatus and method 112 1997
6,102,904 Device for injecting fluid into a wall of a blood vessel 47 1999
 
CORDIS CORPORATION (2)
6,293,959 Balloon catheter and stent delivery system having enhanced stent retention and method 24 1999
6,270,521 Stent delivery catheter system for primary stenting 40 1999
 
EVYSIO MEDICAL DEVICES ULC (2)
6,217,608 Expandable stent and method for delivery of same 126 1999
6,183,506 Expandable stent and method for delivery of same 78 1999
 
IMARX THERAPEUTICS, INC. (2)
2002/0099,356 Transmembrane transport apparatus and method 27 2001
2003/0211,975 Method and apparatus for vascular neuromuscular blockade 2 2003
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (1)
6,190,404 Intravascular stent and method for manufacturing an intravascular stent 89 1998
 
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (1)
6,121,296 Transition-state inhibitors for nucleoside hydrolase and transferase reactions 11 1998
 
ALLERGAN PHARMACEUTICALS HOLDINGS (IRELAND) LIMITED (1)
6,063,768 Application of botulinum toxin to the management of neurogenic inflammatory disorders 94 1997
 
ALLERGAN SALES, INC. (1)
6,319,505 Method for treating dystonia with botulinum toxin types C to G 15 2000
 
BOTULINUM TOXIN RESEARCH ASSOCIATES, INC. (1)
6,429,189 Cytotoxin (non-neurotoxin) for the treatment of human headache disorders and inflammatory diseases 25 1999
 
CEREVAST THERAPEUTICS, INC. (1)
6,579,847 Method and apparatus for vascular neuromuscular blockade 11 2000
 
HORIZON TECHNOLOGY FUNDING COMPANY LLC (1)
6,196,230 Stent delivery system and method of use 83 1998
 
KISSEI PHARMACEUTICAL CO., LTD. (1)
5,385,935 Method for the inhibition of restenosis associated with coronary intervention 36 1993
 
MCW RESEARCH FOUNDATION, INC. (1)
6,057,367 Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses 72 1997
 
MEDSTENT INC. (1)
6,261,318 Expandable stent 37 1998
 
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (1)
5,766,605 Treatment of autonomic nerve dysfunction with botulinum toxin 167 1994
 
NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE (1)
5,851,786 Product and process to regulate actin polymerization 13 1995
 
NOVO RPS ULC (1)
6,344,055 Method for production of an expandable stent 63 2000
 
S.E.T.-SMART ENDOLUMENAL TECHNOLOGIES LTD. (1)
6,238,872 Targeted therapy to a biomedical device 18 1998
 
SOLSTICE NEUROSCIENCES, LLC (1)
6,290,961 Method for treating dystonia with botulinum toxin type B 32 2000
 
WAYNE STATE UNIVERSITY (1)
5,092,841 Method for treating an arterial wall injured during angioplasty 380 1990
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (1)
5,939,070 Hybrid botulinal neurotoxins 49 1996
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
5,562,907 Method to prevent side-effects and insensitivity to the therapeutic uses of toxins 41 1994
6,239,118 Method for preventing restenosis using a substituted adenine derivative 20 1999
6,299,893 Method to reduce hair loss and stimulate hair regrowth 49 2000

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7.5 Year Payment $3600.00 $1800.00 $900.00 Nov 29, 2014
11.5 Year Payment $7400.00 $3700.00 $1850.00 Nov 29, 2018
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