Bi-cyclic pyrimidine inhibitors of TGF.beta.

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May 29, 2007
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Jan 6, 2005
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Mar 26, 2004
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Mar 28, 2003

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Abstract

Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with rheumatoid arthritis ameliorated by inhibition of TGF.beta. activity.

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SCIOS INC	6500 PASEO PADRE PARKWAY FREMONT CA 94555

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A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....

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Inventor Name	Address	# of filed Patents	Total Citations
Axon, Jonathan	Milpitas, CA	2	41
Chakravarty, Sarvajit	Mountain View, CA	146	3328
Conte, Aurelia	Loerrach, DE	27	128
Dugar, Sundeep	San Jose, CA	112	1991
McEnroe, Glenn	San Mateo, CA	15	141
Murphy, Alison	Milpitas, CA	16	279

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Bi-cyclic pyrimidine inhibitors of TGF.beta.

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United States of America Patent

10811428

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PATENT NO	7223766
APP PUB NO	20050004143A1
SERIAL NO	10811428
DOCKET NO

US Family Size	Non-US Coverage
Patent Longevity	Forward Citations

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
May 29, 2007	US,7223766,B2 US7223766B2	GRANTED PATENT AS SECOND PUBLICATION
January 06, 2005	US,20050004143,A1 US20050004143A1	FIRST PUBLISHED PATENT APPLICATION

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10811428

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