Crystallization and purification of macrolides

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United States of America Patent

PATENT NO 7232486
APP PUB NO 20040226501A1
SERIAL NO

10815339

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Abstract

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Provided is a method for crystallization and purification of a macrolide such as tacrolimus, sirolimus, pimecrolimus, or everolimus that includes the step of providing a combination of a macrolide, and a polar solvent, dopolar aprotic solvent, or hydrocarbon solvent at pH of 7 or above.

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Patent Owner(s)

  • TEVA GYOGYSZERGYAR RESZVENYTARSASAG;TEVA PHARMACEUTICALS USA, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Csorvasi, Andrea Debrecen, HU 15 52
Keri, Vilmos Debrecen, HU 43 118

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