Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
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United States of America Patent
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Jun 19, 2007
Issued Date -
N/A
app pub date -
Apr 22, 2005
filing date -
Jan 18, 2000
priority date (Note) -
Expired
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Abstract
Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating, e.g., kinases-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
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