Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof

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United States of America Patent

PATENT NO 7259002
APP PUB NO 20040223959A1
SERIAL NO

10761905

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Abstract

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The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing MGAT3 polypeptides, fragments, and homologues thereof. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

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Patent Owner(s)

  • BRISTOL-MYERS SQUIBB COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jian Princeton, NJ 1536 22502
Cheng, Dong Furlong, PA 21 67
Feder, John N Belle Mead, NJ 150 938
Meegalla, Rupalie Boothwyn, PA 2 0
Nelson, Thomas C Lawrenceville, NJ 37 223
Ramaker, Michael Greenville, DE 2 0

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