Vector system
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United States of America Patent
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-
Aug 21, 2007
Grant Date -
Jan 22, 2004
app pub date -
Apr 7, 2003
filing date -
Oct 6, 2000
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.
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