Use of optical diffraction elements in detection methods
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United States of America Patent
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Aug 21, 2007
Grant Date -
Jul 1, 2004
app pub date -
May 28, 2002
filing date -
May 29, 2001
priority date (Note) -
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Abstract
The invention relates to a method for determining luminescent molecules by means of optical excitation in confocal measurement volumes using a diffractive optical element. The method is particularly suitable for single-molecule determination, e.g. by means of fluorescence correlation spectroscopy or by means of dynamic light scattering. An apparatus suitable for carrying out the method according to the invention is furthermore disclosed.
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