Chemosensitizing with liposomes containing oligonucleotides
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United States of America Patent
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Aug 28, 2007
Grant Date -
Nov 20, 2003
app pub date -
Feb 15, 2002
filing date -
Mar 21, 1997
priority date (Note) -
Expired
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Abstract
The invention relates to the use of oligonucleotide containing cationic liposomal formulations to enhance the efficacy of chemotherapy and/or radiotherapy, particularly as a means to sensitize cancerous tumor tissues to the efficiencies of chemotherapy. This is particularly advantageous in the context of treating raf expressing tumors such as breast, lung, pancreatic and prostate tumors.
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