Adenosine analogues and their use as pharmaceutical agents
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United States of America Patent
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Sep 4, 2007
Grant Date -
Jul 1, 2004
app pub date -
Jun 27, 2003
filing date -
Jun 27, 2002
priority date (Note) -
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Abstract
The present invention relates to compounds according to the general formula (I) ##STR00001## wherein X is selected from the group consisting of ##STR00002## wherein n and p are independently 0, 1, 2, or 3, provided that n+p is a least 1; and unsubstituted and at least monosubstituted C.sub.1-C.sub.10-alkylene-Y, C.sub.2-C.sub.10-alkylene-Y, C.sub.3-C.sub.10-cycloalkylene-Y and C.sub.3-C.sub.10-cycloalkenylene-Y; and R.sup.1, A, B, Q, T, Y, E and W have the meanings given in the description.These compounds are useful for the manufacture of a medicament for the treatment of insulin resistance, type 2 diabetes, metabolic syndrome, lipid disorders or cardiovasular disease or for providing an anti-lipolytic effect.
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