Fusion molecules and treatment of IgE-mediated allergic diseases

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United States of America Patent

PATENT NO 7265208
APP PUB NO 20030082190A1
SERIAL NO

09847208

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Abstract

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The invention concerns bifunctional fusion molecules for the treatment of IgE-mediated allergic conditions and Fc.epsilon.RI-mediated autoimmune conditions. The invention provides a new therapeutic approach for the treatment of both acute and late-phase allergic responses due to ingestion, inhalation, cutaneous and parenteral exposure to allergens, responses including asthma, allergic rhinitis, atopic dermatitis, severe food allergies, chronic urticaria and angioedema, as well as anaphylactic reactions due to exposures such as bee stings or penicillin allergy. In addition, the invention provides for a novel, safer and more efficacious form of allergy vaccination.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY1111 FRANKLIN STREET TWELFTH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Saxon, Andrew Santa Monica, CA 15 124
Zhang, Ke Los Angeles, CA 364 1936
Zhu, Daocheng Los Angeles, CA 7 34

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