Neurotoxins with enhanced target specificity

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United States of America Patent

PATENT NO 7273722
SERIAL NO

09726949

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Abstract

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Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood.

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Patent Owner(s)

Patent OwnerAddress
ALLERGAN INC2525 DUPONT DRIVE IRVINE CA 92612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Kei Roger Coto de Caza, CA 187 4077
Lin, Wei-Jen Cerritos, CA 14 166
Steward, Lance E Irvine, CA 134 2666

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