Compositions and methods for altering biosynthesis of taxanes and taxane-related compounds

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United States of America Patent

PATENT NO 7273755
APP PUB NO 20030175913A1
SERIAL NO

10361290

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Abstract

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Isolated nucleic acid and amino acid sequences for phenylalanine aminomutase enzyme and methods for purifying this enzyme are provided. Methods for altering biosynthesis of compounds in plant cell cultures are also provided. In particular, methods for altering production of taxanes and taxane-related compounds are provided.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYROUTE 206 & PROVINCE LINE ROAD PRINCETON NJ 08543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yijun Madison, CT 24 139
Dougherty, Brian A Killingworth, CT 8 197
Hofstead, Sandra Berlin, NH 1 2
Lam, Kin S San Diego, CA 21 110
Li, Wenying Middletown, CT 46 399
Steele, Christopher L Manlius, NY 4 11
Xing, Zizhuo Syracuse, NY 7 13

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