Nucleic acid molecule comprising a nucleic acid sequence coding for a haemocyanin
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United States of America Patent
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Sep 25, 2007
Grant Date -
Jul 5, 2007
app pub date -
Aug 29, 2006
filing date -
Aug 20, 1999
priority date (Note) -
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Abstract
A nucleic acid molecule or construct alone or with a promoter suitable for expression control is contemplated that codes for a HLH2 haemocyanin polypeptide and comprises at least one intron sequence, as well as haemocyanin fusion proteins. The construct further can comprise a nucleic acid sequence that codes for an antigen. Host cells are also contemplated that contain the nucleic acid molecules or construct and recombinant expression product thereof. The invention further relates to a pharmaceutical composition that comprises the expression product of that nucleic acid and antibodies obtainable by immunization of an animal therewith, as well as use of the antibodies in screening methods for the identification of tumors.
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