.beta.-Secretase variant

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United States of America Patent

PATENT NO 7291495
APP PUB NO 20050026182A1
SERIAL NO

10838854

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Abstract

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The invention provides polynucleotides and polypeptides encoding an isolated amyloid inhibitor protein (APIP) and compositions thereof. The polypeptides of the subject invention can be used to inhibit the catabolism or sequential cleavage of amyloid beta precursor protein (APP) by sequential cleavage of APP by beta secretase and gamma secretase.

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Patent Owner(s)

Patent OwnerAddress
SERONO GENETICS INSTITUTE S AROUTE NATIONALE 7 91000 EVRY FRANCE

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bejanin, Stephane Paris, FR 18 240
Tanaka, Hiroaki Antony, FR 532 5487

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