Activatable probes and methods for in vivo gene detection
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United States of America Patent
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Nov 20, 2007
Grant Date -
Dec 29, 2005
app pub date -
Jan 21, 2005
filing date -
Jun 25, 2001
priority date (Note) -
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Abstract
Probes for detecting a target polynucleotide are provided. One aspect provides a molecular beacon probe set wherein the donor molecular beacon comprises a quantum dot and an acceptor molecular beacon comprises at least one reporter. The probes optionally comprise a protein transduction domain, targeting signal, or a combination thereof. Methods for detecting target polynucleotides using the disclosed probes are also provided.
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