Hybridization-triggered fluorescent detection of nucleic acids
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United States of America Patent
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Nov 20, 2007
Grant Date -
Jul 19, 2007
app pub date -
Oct 3, 2005
filing date -
Oct 26, 1999
priority date (Note) -
Expired
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Abstract
Compositions and methods for fluorescent detection of nucleic acids are provided. The compositions can be detected by fluorescence when hybridized to a nucleic acid containing a target sequence, but are non-fluorescent in the non-hybridized state. Alternatively, the fluorescence properties of the compositions change in a detectable manner upon hybridization to a nucleic acid containing a target sequence. Methods for synthesis and methods of use of the compositions are also provided.
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