Methods for protecting allogeneic islet transplant using soluble CTLA4 mutant molecules
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United States of America Patent
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Dec 4, 2007
Grant Date -
Jan 30, 2003
app pub date -
May 23, 2002
filing date -
May 23, 2001
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Abstract
The present invention is a method of inhibiting islet cell transplant rejection, particularly to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of a soluble CTLA4 mutant molecule is L104EA29YIg.
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