Nucleoside and oligonucleotide analogues
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United States of America Patent
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Jan 1, 2008
Grant Date -
Nov 6, 2003
app pub date -
May 5, 2003
filing date -
Feb 12, 1999
priority date (Note) -
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Abstract
A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): ##STR00001## wherein A represents a C.sub.1-C.sub.4 alkylene group, and B is an unsubstituted purin-9-yl group, an unsubstituted 2-oxo-pyrimidin-1-yl-group, a substituted purin-9-yl-group or a substituted 2-oxo-pyrimidin-1-yl group. Also a method for preventing or treating a disease preventable or treatable by the antisense or antigene activity of an oligonucleotide by administering the oligonucleotide analogue.
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