Medical devices employing triazine compounds and compositions thereof
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United States of America Patent
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Feb 26, 2008
Issued Date -
N/A
app pub date -
Aug 30, 2006
filing date -
Sep 21, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates to methods, compounds, and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses, and is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention also relates to compounds that inhibit smooth muscle proliferation, for example, by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis. This invention also relates to medical devices, such as a stent, comprising a compound or composition of this invention disposed on or within the medical device.
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