Multi-dimensional proteomic analysis method
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United States of America Patent
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Mar 25, 2008
Grant Date -
Oct 24, 2002
app pub date -
Mar 28, 2002
filing date -
Mar 28, 2001
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Abstract
A multi-dimensional proteomic analysis method utilizing cationic electrophoresis is described. The method includes separating proteins in one direction using cationic electrophoresis and separating the proteins in a second orthogonal direction using other electrophoresis separation methods such as denaturing electrophoresis and electrophoresis subsequent to proteolytic cleavage or isofocussing. The two dimensional array may be used to determine various protein-protein interactions in a sample.
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