Bacillus anthracis protective antigen
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United States of America Patent
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Apr 8, 2008
Grant Date -
Jan 24, 2008
app pub date -
Jun 15, 2005
filing date -
Jun 16, 2004
priority date (Note) -
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Abstract
A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinant Bacillus anthracis Protective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinant Bacillus anthracis Protective Antigen (rPA).Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof.The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
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