Induction of a protective immune response through microprojectiles coated with a DNA sequence encoding an immunogenic protein

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United States of America Patent

PATENT NO 7358234
APP PUB NO 20040092019A1
SERIAL NO

10610601

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a process for inducing a protective immune response in a mammal against a virus, in which a construct including a promoter and a DNA sequence encoding a protein or peptide producing an immune response against the virus is introduced into muscle or skin of the mammal via a microprojectile. Sufficient amounts of the construct are administered so as to produce a protective immune response in the mammal.

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Patent Owner(s)

Patent OwnerAddress
DUKE UNIVERSITYDURHAM NC 27705

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johnston, Stephen A Dallas, TX 41 946
Sanford, John C Livonia, NY 31 2069

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