Modulators of melanocortin receptor
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United States of America Patent
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Apr 29, 2008
Grant Date -
Jul 29, 2004
app pub date -
Dec 4, 2003
filing date -
Dec 4, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention provides compounds and methods for treating melanocortin receptor associated disorders, such as weight loss disorders including cachexia resulting from cancer and other chronic illnesses. The compounds are represented by formula I: ##STR00001## wherein X is oxygen or sulfur; G is G1 or G2: ##STR00002## L.sub.1, L.sub.2, L.sub.3 and Q are linker groups, and Rings A, B and C, and R.sup.1-R.sup.14 are described in the specification. The compounds are antagonists of melanocortin receptors.
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