Fusion protein including of CD4
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United States of America Patent
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May 6, 2008
Grant Date -
Dec 30, 2004
app pub date -
Oct 24, 2002
filing date -
Oct 25, 2001
priority date (Note) -
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Abstract
Novel recombinant polypeptides are disclosed herein that include a CD4 polypeptide ligated at its C-terminus with a portion of an immunoglobulin comprising a hinge region and a constant domain of a mammalian immunoglobulin heavy chain. The portion or the IgG is fused at its C-terminus with a polypeptide comprising a tailpiece from the C-terminus of the heavy chain of an IgA antibody ara tailpiece from a C-terminus of the heavy chain of an IgM antibody. Also disclosed herein are methods for using these CD4 fusion proteins.
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