US Patent No: 7,368,126
Number of patents in Portfolio can not be more than 2000
Controlled release depot formulations
Stats
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May 6, 2008
Issued date -
Nov 4, 2003
filing date -
10/701,939
serial no -
In Force
status
Importance
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Abstract
Methods and compositions for systemically or locally administering a beneficialagent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a prolonged duration of time. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 4,865,845 Release rate adjustment of osmotic or diffusional delivery devices | 96 | 1987 | |
| 5,112,614 Implantable delivery dispenser | 88 | 1989 | |
| 5,057,318 Delivery system for beneficial agent over a broad range of rates | 109 | 1990 | |
| 5,059,423 Delivery system comprising biocompatible beneficial agent formulation | 91 | 1990 | |
| 5,137,727 Delivery device providing beneficial agent stability | 103 | 1991 | |
| 5,209,746 Osmotically driven delivery devices with pulsatile effect | 45 | 1992 | |
| 5,234,692 Delivery device with a protective sleeve | 82 | 1992 | |
| 5,234,693 Delivery device with a protective sleeve | 81 | 1992 | |
| 5,308,348 Delivery devices with pulsatile effect | 68 | 1993 | |
| 5,456,679 Delivery devices with pulsatile effect | 41 | 1994 | |
| 5,620,700 Injectable drug delivery system and method | 45 | 1995 | |
| 2005/0281,879 Excipients in drug delivery vehicles | 2 | 2004 | |
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| 5,151,093 Osmotically driven syringe with programmable agent delivery | 25 | 1990 | |
| 6,130,200 Gel composition and methods | 59 | 1997 | |
| 6,331,311 Injectable depot gel composition and method of preparing the composition | 41 | 1997 | |
| 2003/0180,364 Catheter injectable depot compositions and uses thereof | 10 | 2002 | |
| 2004/0024,069 Injectable depot compositions and uses thereof | 11 | 2002 | |
| 2004/0001,889 Short duration depot formulations | 15 | 2003 | |
| 2004/0022,859 Injectable multimodal polymer depot compositions and uses thereof | 9 | 2003 | |
| 2005/0106,214 Excipients in drug delivery vehicles | 6 | 2004 | |
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| 4,938,763 Biodegradable in-situ forming implants and methods of producing the same | 378 | 1988 | |
| 5,278,201 Biodegradable in-situ forming implants and methods of producing the same | 221 | 1990 | |
| 5,599,552 Biodegradable polymer composition | 78 | 1994 | |
| 5,733,950 Biodegradable in-situ forming implants and methods of producing the same | 65 | 1995 | |
| 5,780,044 Liquid delivery compositions | 73 | 1996 | |
| 5,990,194 Biodegradable in-situ forming implants and methods of producing the same | 67 | 1997 | |
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| 5,468,253 Elastomeric medical device | 150 | 1993 | |
| 5,713,920 Elastomeric medical device | 39 | 1995 | |
| 5,639,851 High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers | 13 | 1995 | |
| 5,714,551 High strength, melt processable, lactide-rich, poly (lactide-co-p-dioxanone) copolymers | 47 | 1996 | |
| 5,868,788 High-strength, melt-processable, lactade-rich, poly(lactade-co-p-dioxanone) copolymers | 4 | 1997 | |
| 6,113,624 Absorbable elastomeric polymer | 17 | 1999 | |
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| 5,656,297 Modulated release from biocompatible polymers | 118 | 1994 | |
| 5,654,010 Composition for sustained release of human growth hormone | 91 | 1995 | |
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| 4,443,340 Control of iron induced fouling in water systems | 37 | 1983 | |
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| 2005/0190,527 SPRING CONTACT SYSTEM FOR EMI FILTERED HERMETIC SEALS FOR ACTIVE IMPLANTABLE MEDICAL DEVICES | 2005 | ||
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| 5,651,986 Controlled local delivery of chemotherapeutic agents for treating solid tumors | 79 | 1996 | |
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| 5,310,865 Polyhydroxycarboxylic acid and preparation process thereof | 44 | 1992 | |
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| 4,985,404 Prolonged release of biologically active polypeptides | 24 | 1988 | |
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| 5,336,057 Micropump with liquid-absorptive polymer gel actuator | 23 | 1993 | |
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| 5,556,905 Physically-modified degradable thermoplastic compositions | 15 | 1994 | |
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| 4,853,218 Zinc-protamine-alpha interferon complex | 24 | 1987 | |
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| 5,279,608 Osmotic pumps | 68 | 1991 | |
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| 5,085,866 Method of producing zero-order controlled-released devices | 23 | 1988 | |
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| 5,242,910 Sustained release compositions for treating periodontal disease | 25 | 1992 | |
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| 2003/0170,289 Injectable depot compositions and uses thereof | 7 | 2002 | |
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| 6,432,438 Biodegradable vehicle and filler | 28 | 2000 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Nov 6, 2015 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Nov 6, 2019 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |