Controlled release depot formulations

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7368126
APP PUB NO 20040151753A1
SERIAL NO

10701939

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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Methods and compositions for systemically or locally administering a beneficialagent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a prolonged duration of time. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DURECT CORPORATIONCUPERTINO, CA67

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bannister, Roy Hollister, CA 2 145
Chen, Guohua Sunnyvale, CA 85 1420
Houston, Paul Hayward, CA 6 190
Kameda, Teresa Sunnyvale, CA 1 74
Kleiner, Lothar Los Altos, CA 37 681
Priebe, David Seattle, WA 4 138

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
6432438 Biodegradable vehicle and filler 57 2000
 
Nippon Densan Corporation (1)
5336057 Micropump with liquid-absorptive polymer gel actuator 36 1993
 
SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (1)
5279608 Osmotic pumps 107 1991
 
ALZA CORPORATION (12)
4865845 Release rate adjustment of osmotic or diffusional delivery devices 167 1987
5112614 Implantable delivery dispenser 171 1989
5057318 Delivery system for beneficial agent over a broad range of rates 182 1990
5059423 Delivery system comprising biocompatible beneficial agent formulation 165 1990
5137727 Delivery device providing beneficial agent stability 175 1991
5209746 Osmotically driven delivery devices with pulsatile effect 55 1992
5234692 Delivery device with a protective sleeve 153 1992
5234693 Delivery device with a protective sleeve 154 1992
5308348 Delivery devices with pulsatile effect 80 1993
5456679 Delivery devices with pulsatile effect 55 1994
5620700 Injectable drug delivery system and method 57 1995
2005/0281,879 Excipients in drug delivery vehicles 6 2004
 
ATRIX LABORATORIES, INC. (6)
4938763 Biodegradable in-situ forming implants and methods of producing the same 542 1988
5278201 Biodegradable in-situ forming implants and methods of producing the same 295 1990
5599552 Biodegradable polymer composition 132 1994
5733950 Biodegradable in-situ forming implants and methods of producing the same 102 1995
5780044 Liquid delivery compositions 141 1996
5990194 Biodegradable in-situ forming implants and methods of producing the same 116 1997
 
SOUTHERN RESEARCH INSTITUTE (1)
5085866 Method of producing zero-order controlled-released devices 24 1988
 
Alkermes Controlled Therapeutics, Inc. (2)
5656297 Modulated release from biocompatible polymers 183 1994
5654010 Composition for sustained release of human growth hormone 103 1995
 
REILLY INDUSTRIES, INC. (1)
5556905 Physically-modified degradable thermoplastic compositions 17 1994
 
SCHERING CORPORATION (1)
4853218 Zinc-protamine-alpha interferon complex 27 1987
 
MONSANTO TECHNOLOGY LLC (1)
4985404 Prolonged release of biologically active polypeptides 28 1988
 
The Procter & Gamble Company (1)
5242910 Sustained release compositions for treating periodontal disease 33 1992
 
TIMKEN COMPANY, THE (1)
2003/0170,289 Injectable depot compositions and uses thereof 21 2002
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
5651986 Controlled local delivery of chemotherapeutic agents for treating solid tumors 112 1996
 
BETZ LABORATORIES, INC. (1)
4443340 Control of iron induced fouling in water systems 38 1983
 
DURECT CORPORATION (8)
5151093 Osmotically driven syringe with programmable agent delivery 34 1990
6130200 Gel composition and methods 109 1997
6331311 Injectable depot gel composition and method of preparing the composition 122 1997
2003/0180,364 Catheter injectable depot compositions and uses thereof 19 2002
2004/0024,069 Injectable depot compositions and uses thereof 24 2002
2004/0001,889 Short duration depot formulations 41 2003
2004/0022,859 Injectable multimodal polymer depot compositions and uses thereof 23 2003
2005/0106,214 Excipients in drug delivery vehicles 11 2004
 
RadioMed Corporation (1)
8320995 Fiducial marker with rings 7 2007
 
ETHICON, INC. (6)
5468253 Elastomeric medical device 430 1993
5713920 Elastomeric medical device 167 1995
5639851 High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers 26 1995
5714551 High strength, melt processable, lactide-rich, poly (lactide-co-p-dioxanone) copolymers 56 1996
5868788 High-strength, melt-processable, lactade-rich, poly(lactade-co-p-dioxanone) copolymers 5 1997
6113624 Absorbable elastomeric polymer 46 1999
 
MITSUI CHEMICALS, INC. (1)
5310865 Polyhydroxycarboxylic acid and preparation process thereof 59 1992
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
SMITH & NEPHEW ORTHOPAEDICS AG (7)
* 2009/0030,525 METHOD FOR RESTORING A DAMAGED OR DEGENERATED INTERVERTEBRAL DISC 5 2008
8747899 Injectable in situ self-forming mineral-polymer hybrid composition and uses thereof 4 2009
8389467 In situ self-setting mineral-polymer hybrid materials, composition and use thereof 6 2009
8920842 Temperature controlled and pH dependent self gelling biopolymeric aqueous solution 0 2009
* 2010/0028,434 Temperature controlled and pH dependent self gelling biopolymeric aqueous solution 0 2009
8258117 Composition and method for the repair and regeneration of cartilage and other tissues 2 2010
* 2011/0086,008 COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES 2 2010
 
PIRAMAL HEALTHCARE (CANADA) LTS. (2)
* 2007/0037,737 Composition and method for the repair and regeneration of cartilage and other tissues 29 2006
* 2009/0075,383 COMPOSITION AND METHOD FOR EFFICIENT DELIVERY OF NUCLEIC ACIDS TO CELLS USING CHITOSAN 5 2006
 
DURECT CORPORATION (2)
* 2006/0141,040 Injectable non-aqueous suspension 22 2005
* 2014/0141,086 Injectable Depot Compositions and Uses Thereof 0 2013
 
ASTRAZENECA PHARMACEUTICALS LP (2)
8895033 Sustained release formulations using non-aqueous carriers 0 2009
* 2011/0212,138 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS CARRIERS 0 2009
 
BIOSYNTECH CANADA INC. (2)
* 2010/0029,549 SITU SELF-SETTING MINERAL-POLYMER HYBRID MATERIALS, COMPOSITION AND USE THEREOF 3 2009
* 2010/0021,545 INJECTABLE IN SITU SELF-FORMING MINERAL-POLYMER HYBRID COMPOSITION AND USES THEREOF 5 2009
 
SURMODICS, INC. (1)
9090737 Viscous terpolymers as drug delivery platform 3 2008
 
ALLERGAN, INC. (7)
* 8425929 Sustained release intraocular implants and methods for preventing retinal dysfunction 2 2004
* 2005/0244,479 Sustained release intraocular implants and methods for preventing retinal dysfunction 33 2004
* 2008/0131,485 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR PREVENTING RETINAL DYSFUNCTION 16 2007
8580292 Sustained release intraocular implants and methods for treating ocular vasculopathies 0 2008
* 2008/0118,549 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR TREATING OCULAR VASCULOPATHIES 10 2008
9144543 Sustained release intraocular implants and methods for preventing retinal dysfunction 0 2013
9138480 Compositions and methods for stimulating hair growth 0 2014
 
SURMODICS PHARMACEUTICALS, INC. (10)
9415197 Implantable suction cup composites and implants comprising same 0 2009
8974808 Elastic implantable composites and implants comprising same 2 2009
8951546 Flexible implantable composites and implants comprising same 3 2009
* 2010/0158,978 BIOACTIVE SPRAY COATING COMPOSITIONS AND METHODS OF MAKING AND USES THEREOF 8 2009
* 2010/0160,891 ELASTIC IMPLANTABLE COMPOSITES AND IMPLANTS COMPRISING SAME 9 2009
* 2010/0168,807 BIOACTIVE TERPOLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME 8 2009
9598532 Terpolymers as pressure-sensitive adhesives 0 2011
* 8920921 Terpolymer blends and their use as pressure-sensitive adhesives 4 2011
8900699 Terpolymer blends and their use as pressure-sensitive adhesives 0 2011
* 2012/0077,028 TERPOLYMER BLENDS AND THEIR USE AS PRESSURE-SENSITIVE ADHESIVES 7 2011
 
Brookwood Pharmaceuticals (1)
* 2011/0129,422 Viscous Terpolymers as Drug Delivery Platform 8 2011
 
WARSAW ORTHOPEDIC, INC. (2)
* 8591935 Methods and compositions for treating pain comprising a statin 0 2011
* 2011/0217,382 Methods and Compositions for Treating Pain Comprising a Statin 0 2011
 
UNIVERSITY OF DELAWARE (1)
9597412 Injectable delivery system for heparan-binding growth factors 0 2012
 
BROOKWOOD PHARMACEUTICALS, INC. (1)
* 2009/0124,535 VISCOUS TERPOLYMERS AS DRUG DELIVERY PLATFORM 13 2008
* Cited By Examiner

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