Selective genome amplification

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United States of America Patent

PATENT NO 7368265
APP PUB NO 20070190556A1
SERIAL NO

11656762

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Abstract

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The invention provides methods and compositions for amplifying selected polynucleotides, especially selected subsets of restriction fragments. Generally, methods of the invention are implemented by ligating adaptors containing at least one promoter sequence to such fragments under conditions that promote the formation of closed single stranded or double stranded structures, which are capable of serving as cyclical templates for transcription.

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Patent Owner(s)

Patent OwnerAddress
AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH ("A*STAR")1 FUSIONOPOLIS WAY #21-10 CONNEXIS NORTH TOWER SINGAPORE 138632

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brenner, Sydney Ely, GB 108 21860
Macevicz, Stephen C Cupertino, CA 36 5488
Mikawa, Gi Cambridge, GB 30 1904

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